| Title | [Diffuse alveolar hemorrhage after allogeneic bone marrow transplantation] |
| Author(s) | Ishida T, Arita M, Fujimori N |
| Institution | Department of Internal Medicine, Kurashiki Central Hospital, Japan. |
| Source | Nihon Kyobu Shikkan Gakkai Zasshi 1996 Mar; 34(3):369-73. |
| MeSH | Adult Bone Marrow Transplantation Bronchoalveolar Lavage Fluid English Abstract Female Hemorrhage Humans Lung Diseases Lymphoma, T-Cell Pulmonary Alveoli
|
| Abstract | A 44-year-old woman with malignant T-cell lymphoma and secondary leukemia received an allogeneic bone marrow transplant (BMT). She had received BMT conditioning treatment with total body irradiation and chemotherapy. Hemoptysis and progressive dyspnea developed 11 days after the transplant. A chest roentgenogram showed bilateral diffuse infiltrates. Bronchoalveolar lavage fluid was bloody, and diffuse alveolar hemorrhage (DAH) was diagnosed. Respiratory failure progressed despite mechanical ventilation and administration of corticosteroids. The patient died 58 days after the transplant DAH after BMT has been recognized in western countries as a syndrome with high mortality. We draw attention to the fact that DAH is a serious early pulmonary complication of BMT also in Japan. |
| Language | jpn |
| Pub Type(s) | Case Reports Journal Article
|
| PubMed ID | 8778482 |