| Title | Benzonatate for opioid-resistant cough in advanced cancer. |
| Author(s) | Doona M, Walsh D |
| Institution | Palliative Care Programme (a World Health Organization Demonstration Project, Cleveland, OH, USA. |
| Source | Palliat Med 1998 Jan; 12(1):55-8. |
| MeSH | Adenocarcinoma
Adult
Aged
Antitussive Agents
Butylamines
Carcinoma, Non-Small-Cell Lung
Colonic Neoplasms
Cough
Drug Resistance
Female
Humans
Lung Neoplasms
Male
Neoplasms, Unknown Primary
Treatment Outcome
|
| Abstract | Chronic cough is a distressing symptom experienced by approximately 37% of patients with advanced cancer. Palliation of chronic nonproductive cough should always first address the underlying cause but in some patients chronic, nonproductive cough persists and antitussive agents are required. Opioids are the gold standard cough suppressants, of which codeine is the most widely used; patients with an opioid-resistant cough often prove to be a therapeutic challenge. We report three patients with an opioid-resistant cough who achieved symptomatic relief with the peripherally acting nonopioid drug benzonatate. |
| Language | eng |
| Pub Type(s) | Case Reports
Journal Article
|
| PubMed ID | 9616460 |
