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| Periclou AP, Nandy P, Avramis VI
Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT). [Journal Article]
In Vivo 2000 May-Jun; 14(3):377-88.
Abstract | Full Citation | Find Related Articles | | Boyer PL, Sarafianos SG, Arnold E, et al.
Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision. [Journal Article]
J Virol 2002 Sep; 76(18):9143-51.
Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Avramis VI, Kwock R, Avramis IA, et al.
Synergistic antiviral effect of PEG-asparaginase (ONCASPAR), with protease inhibitor alone and in combination with RT inhibitors against HIV-1 infected T-cells: a model of HIV-1-induced T-cell lymphoma. [Journal Article]
In Vivo 2001 Jan-Feb; 15(1):1-9.
Abstract | Full Citation | Find Related Articles | | Avramis VI, Kwock R, Solorzano MM, et al.
Evidence of in vitro development of drug resistance to azidothymidine in T-lymphocytic leukemia cell lines (Jurkat E6-1/AZT-100) and in pediatric patients with HIV-1 infection. [Journal Article]
J Acquir Immune Defic Syndr 1993 Dec; 6(12):1287-96.
Abstract | Full Citation | Find Related Articles | | White EL, Parker WB, Ross LJ, et al.
Lack of synergy in the inhibition of HIV-1 reverse transcriptase by combinations of the 5'-triphosphates of various anti-HIV nucleoside analogs. [Journal Article]
Antiviral Res 1993 Dec; 22(4):295-308.
Abstract | Full Citation | Find Related Articles | | Odriozola L, Cruchaga C, Andréola M, et al.
Non-nucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3'-azido-3'-deoxythymidine (AZT)-resistant polymerase to AZT-5'-triphosphate. [Journal Article]
J Biol Chem 2003 Oct 24; 278(43):42710-6.
Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Törnevik Y, Ullman B, Balzarini J, et al.
Cytotoxicity of 3'-azido-3'-deoxythymidine correlates with 3'-azidothymidine-5'-monophosphate (AZTMP) levels, whereas anti-human immunodeficiency virus (HIV) activity correlates with 3'-azidothymidine-5'-triphosphate (AZTTP) levels in cultured CEM T-lymphoblastoid cells. [Journal Article]
Biochem Pharmacol 1995 Mar 15; 49(6):829-37.
Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Boyer PL, Sarafianos SG, Arnold E, et al.
Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase. [Journal Article]
J Virol 2001 May; 75(10):4832-42.
Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Taylor DL, Ahmed PS, Tyms AS, et al.
Drug resistance and drug combination features of the human immunodeficiency virus inhibitor, BCH-10652 [(+/-)-2'-deoxy-3'-oxa-4'-thiocytidine, dOTC]. [Journal Article]
Antivir Chem Chemother 2000 Jul; 11(4):291-301.
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