| Pauwels PJ, Colpaert FC
Disparate ligand-mediated Ca(2+) responses by wild-type, mutant Ser(200)Ala and Ser(204)Ala alpha(2A)-adrenoceptor: G(alpha15) fusion proteins: evidence for multiple ligand-activation binding sites. [Journal Article]
Br J Pharmacol 2000 Aug; 130(7):1505-12.
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| Pauwels PJ, Colpaert FC
Heterogeneous ligand-mediated Ca(++) responses at wt and mutant alpha(2A)-adrenoceptors suggest multiple ligand activation binding sites at the alpha(2A)-adrenoceptor. [Journal Article]
Neuropharmacology 2000 Aug 23; 39(11):2101-11.
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| Pauwels PJ, Wurch T, Tardif S, et al.
Analysis of ligand activation of alpha 2-adrenoceptor subtypes under conditions of equal G alpha protein stoichiometry. [Journal Article]
Naunyn Schmiedebergs Arch Pharmacol 2001 May; 363(5):526-36.
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| Pauwels PJ, Tardif S, Colpaert FC, et al.
Modulation of ligand responses by coupling of alpha(2A)-adrenoceptors to diverse G(alpha)-proteins. [Journal Article]
Biochem Pharmacol 2001 May 1; 61(9):1079-92.
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| Pauwels PJ, Tardif S
Enhanced stability of wild-type and constitutively active alpha(2A)-adrenoceptors by ligands with agonist, silent and inverse agonist properties. [Journal Article]
Naunyn Schmiedebergs Arch Pharmacol 2002 Aug; 366(2):134-41.
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| Pauwels PJ, Colpaert FC
Partial to complete antagonism by putative antagonists at the wild-type alpha(2C)-adrenoceptor based on kinetic analyses of agonist:antagonist interactions. [Journal Article]
Br J Pharmacol 2000 Dec; 131(7):1385-90.
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| Pauwels PJ, Tardif S, Wurch T, et al.
Facilitation of constitutive alpha(2A)-adrenoceptor activity by both single amino acid mutation (Thr(373)Lys) and g(alphao) protein coexpression: evidence for inverse agonism. [In Vitro , Journal Article]
J Pharmacol Exp Ther 2000 Feb; 292(2):654-63.
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| Pauwels PJ, Tardif S, Finana F, et al.
Ligand-receptor interactions as controlled by wild-type and mutant Thr(370)Lys alpha2B-adrenoceptor-Galpha15 fusion proteins. [Journal Article]
J Neurochem 2000 Jan; 74(1):375-84.
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| Pauwels PJ, Rauly I, Wurch T
Dissimilar pharmacological responses by a new series of imidazoline derivatives at precoupled and ligand-activated alpha 2A-adrenoceptor states: evidence for effector pathway-dependent differential antagonism. [Journal Article]
J Pharmacol Exp Ther 2003 Jun; 305(3):1015-23.
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