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Pandharipande PP, Pun BT, Herr DL, et al. 
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. [Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.]
JAMA 2007 Dec 12; 298(22):2644-53.
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Ely EW, Shintani A, Truman B, et al. 
Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. [Journal Article]
JAMA 2004 Apr 14; 291(14):1753-62.
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Masica AL, Girard TD, Wilkinson GR, et al. 
Clinical sedation scores as indicators of sedative and analgesic drug exposure in intensive care unit patients. [JOURNAL ARTICLE]
Am J Geriatr Pharmacother 2007 Sep; 5(3):218-231.
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Ely EW, Truman B, Shintani A, et al. 
Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS). [Journal Article, Validation Studies]
JAMA 2003 Jun 11; 289(22):2983-91.
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McCollam JS, O'Neil MG, Norcross ED, et al. 
Continuous infusions of lorazepam, midazolam, and propofol for sedation of the critically ill surgery trauma patient: a prospective, randomized comparison. [Clinical Trial, Journal Article, Randomized Controlled Trial]
Crit Care Med 1999 Nov; 27(11):2454-8.
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Barletta JF, Devlin JW 
Sedation with dexmedetomidine vs lorazepam in mechanically ventilated patients. [Comment, Letter]
JAMA 2008 Apr 2; 299(13):1541-2; author reply 1542.
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Carson SS, Kress JP, Rodgers JE, et al. 
A randomized trial of intermittent lorazepam versus propofol with daily interruption in mechanically ventilated patients. [Journal Article, Multicenter Study, Randomized Controlled Trial]
Crit Care Med 2006 May; 34(5):1326-32.
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Swart EL, van Schijndel RJ, van Loenen AC, et al. 
Continuous infusion of lorazepam versus medazolam in patients in the intensive care unit: sedation with lorazepam is easier to manage and is more cost-effective. [Clinical Trial, Journal Article, Randomized Controlled Trial]
Crit Care Med 1999 Aug; 27(8):1461-5.
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Ely EW, Inouye SK, Bernard GR, et al. 
Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). [Journal Article, Validation Studies]
JAMA 2001 Dec 5; 286(21):2703-10.
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