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Galiè N, Rubin Lj, Hoeper M, et al. 
Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial. [Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't]
Lancet 2008 Jun 21; 371(9630):2093-100.
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Channick RN, Simonneau G, Sitbon O, et al. 
Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. [Clinical Trial, Journal Article, Multicenter Study, Randomized Controlled Trial]
Lancet 2001 Oct 6; 358(9288):1119-23.
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Rubin LJ, Badesch DB, Barst RJ, et al. 
Bosentan therapy for pulmonary arterial hypertension. [Clinical Trial, Journal Article, Multicenter Study, Randomized Controlled Trial]
N Engl J Med 2002 Mar 21; 346(12):896-903.
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Barst RJ, Langleben D, Badesch D, et al. 
Treatment of pulmonary arterial hypertension with the selective endothelin-A receptor antagonist sitaxsentan. [Journal Article, Multicenter Study, Randomized Controlled Trial]
J Am Coll Cardiol 2006 May 16; 47(10):2049-56.
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Denton CP, Humbert M, Rubin L, et al. 
Bosentan therapy for pulmonary arterial hypertension related to connective tissue disease: a subgroup analysis of the pivotal clinical trials and their open-label extensions. [JOURNAL ARTICLE]
Ann Rheum Dis 2006 Jun 22.
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Galiè N, Beghetti M, Gatzoulis MA, et al. 
Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. [Journal Article, Multicenter Study, Randomized Controlled Trial]
Circulation 2006 Jul 4; 114(1):48-54.
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Ibrahim R, Granton JT, Mehta S 
An open-label, multicentre pilot study of bosentan in pulmonary arterial hypertension related to congenital heart disease. [Journal Article]
Can Respir J 2006 Dec; 13(8):415-20.
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Sitbon O, Badesch DB, Channick RN, et al. 
Effects of the dual endothelin receptor antagonist bosentan in patients with pulmonary arterial hypertension: a 1-year follow-up study. [Journal Article, Multicenter Study]
Chest 2003 Jul; 124(1):247-54.
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King Jr TE, Behr J, Brown KK, et al. 
A Randomized Placebo-Controlled Trial of Bosentan in Patients with Idiopathic Pulmonary Fibrosis. [JOURNAL ARTICLE]
Am J Respir Crit Care Med 2007 Sep 27.
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