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| Small DS, Farid NA, Li YG, et al. Effect of ranitidine on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel. [JOURNAL ARTICLE] Curr Med Res Opin 2008 Aug; 24(8):2251-2257. Abstract | Full Citation | Find Related Articles | | Payne CD, Li YG, Small DS, et al. Increased Active Metabolite Formation Explains the Greater Platelet Inhibition With Prasugrel Compared to High-dose Clopidogrel. [JOURNAL ARTICLE] J Cardiovasc Pharmacol 2007 Nov; 50(5):555-562. Abstract | Full Citation | | Small DS, Farid NA, Payne CD, et al. Effects of the Proton Pump Inhibitor Lansoprazole on the Pharmacokinetics and Pharmacodynamics of Prasugrel and Clopidogrel. [JOURNAL ARTICLE] J Clin Pharmacol 2008 Feb 26. Abstract | Full Citation | Find Related Articles | | Wallentin L, Varenhorst C, James S, et al. Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease. [JOURNAL ARTICLE] Eur Heart J 2007 Nov 30. Abstract | Full Citation | Find Related Articles | | Wiviott SD, Trenk D, Frelinger AL, et al. Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial. [Journal Article, Research Support, Non-U.S. Gov't] Circulation 2007 Dec 18; 116(25):2923-32. Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Farid NA, Payne CD, Small DS, et al. Cytochrome P450 3A Inhibition by Ketoconazole Affects Prasugrel and Clopidogrel Pharmacokinetics and Pharmacodynamics Differently. [JOURNAL ARTICLE] Clin Pharmacol Ther 2007 Mar 14. Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Brandt JT, Payne CD, Wiviott SD, et al. A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation. [Journal Article, Research Support, Non-U.S. Gov't] Am Heart J 2007 Jan; 153(1):66.e9-16. Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Asai F, Jakubowski JA, Naganuma H, et al. Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: A single ascending dose study in healthy humansdagger. [Journal Article] Platelets 2006 Jun; 17(4):209-17. Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Payne CD, Li YG, Brandt JT, et al. Switching directly to prasugrel from clopidogrel results in greater inhibition of platelet aggregation in aspirin-treated subjects. [Journal Article] Platelets 2008 Jun; 19(4):275-81. Abstract | Full Citation |  |
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