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Mao JH, Kim IJ, Wu D, et al. 
FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression. [Journal Article]
Science 2008 Sep 12; 321(5895):1499-502.
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Steelman LS, Navolanic PM, Sokolosky ML, et al. 
Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors. [JOURNAL ARTICLE]
Oncogene 2008 Mar 10.
Abstract | Full Citation
Akhoondi S, Sun D, von der Lehr N, et al. 
FBXW7/hCDC4 is a general tumor suppressor in human cancer. [Journal Article, Research Support, Non-U.S. Gov't]
Cancer Res 2007 Oct 1; 67(19):9006-12.
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Lu KH, Wu W, Dave B, et al. 
Loss of tuberous sclerosis complex-2 function and activation of Mammalian target of rapamycin signaling in endometrial carcinoma. [Journal Article]
Clin Cancer Res 2008 May 1; 14(9):2543-50.
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Gu Z, Inomata K, Ishizawa K, et al. 
The FBXW7 beta-form is suppressed in human glioma cells. [JOURNAL ARTICLE]
Biochem Biophys Res Commun 2007 Jan 24.
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Fujii Y, Yada M, Nishiyama M, et al. 
Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation. [Journal Article]
Cancer Sci 2006 Aug; 97(8):729-36.
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Zhou J, Wulfkuhle J, Zhang H, et al. 
Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance. [Journal Article]
Proc Natl Acad Sci U S A 2007 Oct 9; 104(41):16158-63.
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DeGraffenried LA, Fulcher L, Friedrichs WE, et al. 
Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway. [Journal Article]
Ann Oncol 2004 Oct; 15(10):1510-6.
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Mao JH, Perez-Losada J, Wu D, et al. 
Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene. [Journal Article]
Nature 2004 Dec 9; 432(7018):775-9.
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