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| Raza A, Sham YY, Vince R Design and synthesis of sulfoximine based inhibitors for HIV-1 protease. [JOURNAL ARTICLE] Bioorg Med Chem Lett 2008 Sep 13. Abstract | Full Citation | Find Related Articles | | Lu D, Vince R Discovery of potent HIV-1 protease inhibitors incorporating sulfoximine functionality. [JOURNAL ARTICLE] Bioorg Med Chem Lett 2007 Aug 23. Abstract | Full Citation | | Specker E, Böttcher J, Brass S, et al. Unexpected Novel Binding Mode of Pyrrolidine-Based Aspartyl Protease Inhibitors: Design, Synthesis and Crystal Structure in Complex with HIV Protease. [JOURNAL ARTICLE] ChemMedChem 2006 Jan 16; 1(1):106-117. Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Ghosh AK, Swanson LM, Cho H, et al. Structure-based design: synthesis and biological evaluation of a series of novel cycloamide-derived HIV-1 protease inhibitors. [Journal Article] J Med Chem 2005 May 19; 48(10):3576-85. Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Rutenber EE, McPhee F, Kaplan AP, et al. A new class of HIV-1 protease inhibitor: the crystallographic structure, inhibition and chemical synthesis of an aminimide peptide isostere. [Journal Article] Bioorg Med Chem 1996 Sep; 4(9):1545-58. Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Pyring D, Lindberg J, Rosenquist A , et al. Design and synthesis of potent C(2)-symmetric diol-based HIV-1 protease inhibitors: effects of fluoro substitution. [Journal Article] J Med Chem 2001 Sep 13; 44(19):3083-91. Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Tyndall JD, Reid RC, Tyssen DP, et al. Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease. [Journal Article] J Med Chem 2000 Sep 21; 43(19):3495-504. Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Ghosh AK, Chapsal BD, Weber IT, et al. Design of HIV Protease Inhibitors Targeting Protein Backbone: An Effective Strategy for Combating Drug Resistance. [JOURNAL ARTICLE] Acc Chem Res 2007 Aug 28. Abstract | Full Citation | | Myers AG, Barbay JK, Zhong B Asymmetric synthesis of chiral organofluorine compounds: use of nonracemic fluoroiodoacetic acid as a practical electrophile and its application to the synthesis of monofluoro hydroxyethylene dipeptide isosteres within a novel series of HIV protease inhibitors. [Journal Article] J Am Chem Soc 2001 Aug 1; 123(30):7207-19. Abstract | Full Citation | Publisher Full Text | Find Related Articles |  |
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