(Tracrium)
2,858 results
  • Cataract Extraction in a White-Bellied Caique (Pionites leucogaster): A Case Report. [Case Reports]
    Vet Ophthalmol. 2026 Sep; 29(5):e70263.Kerdchuchuen K, Tuntivanich NVO
  • A four-year-old female white-bellied caique (Pionites leucogaster) was presented with lens opacification and blindness in the right eye (OD) following a history of head trauma. The left eye (OS) was normal. The bird underwent general anesthesia. Intracameral atracurium was administered to induce pupil dilation. Following corneal incision, ophthalmic viscoelastic devices (OVDs) were injected, and …
  • Anesthetic adaptations for robotic-assisted pediatric surgery in a resource-constrained setting: a case report. [Case Reports]
    Int J Surg Case Rep. 2026 Aug; 138(8):2876-2879.Aspi MTB, Nuñez JPMIJ
  • CONCLUSIONS: This case highlights the conditional feasibility of pediatric robotic-assisted surgery in a resource-limited setting when performed on a carefully selected patient. Safety under such constraints depends on meticulous preparation, anticipation of physiologic challenges, monitoring redundancy, and adaptive anesthetic strategies. As robotic surgical platforms become increasingly adopted in developing countries, strengthening perioperative infrastructure and support systems remains essential to ensure patient safety.
  • Anaesthetic Management of a Child With Severe Spastic Quadriplegic Cerebral Palsy: A Case Report. [Case Reports]
    Cureus. 2026 May; 18(5):e109780.Rai M, Gore R, Setu PC
  • Patients with cerebral palsy are known to present with numerous anaesthetic challenges due to spasticity, joint deformities, cognitive dysfunction, and behavioural abnormalities. Our patient was an eight-year-old girl with severe spastic quadriplegic cerebral palsy (SQCP) posted for cataract surgery with IOL (intraocular lens) placement under general anaesthesia. A thorough preanaesthetic checkup…
  • Allergic reactions to anaesthetics in surgery: current challenges and perspectives. [Review]
    Drug Metab Pers Ther. 2026 Sep 01; 41(3):125-135.Zofia Lisiecka M, Luczak JDM
  • CONCLUSIONS: Currently, the most commonly used local anaesthetics are amides, including lidocaine, bupivacaine, articaine, mepivacaine, ropivacaine, and levobupivacaine. These are considered safer in terms of allergenicity compared to their ester-based predecessors - novocaine, benzocaine, and tetracaine - as their metabolites rarely act as allergens. Among general anaesthetics, intravenous agents such as propofol, midazolam, etomidate, and ketamine, as well as inhalational agents including sevoflurane, isoflurane, desflurane, and xenon, are widely used. These are generally safer than their predecessor, thiopental, with xenon currently exhibiting the highest safety profile due to its inert chemical properties. Muscle relaxants have the highest allergenic potential, as their mechanism of action - blocking acetylcholine receptors - can lead to cell damage and the release of immune-stimulating substances. The only representative of depolarising muscle relaxants is succinylcholine, while non-depolarising agents include atracurium, cisatracurium, vecuronium, rocuronium, pancuronium, and mivacurium.Preventive measures to reduce the risk of AR include: a detailed patient history and diagnostic testing using skin tests, provocation tests, and/or blood tests for immunoglobulin E (IgE); replacement of the allergenic drug with a safer alternative if an allergy is confirmed; close monitoring for allergic manifestations during surgery, with professional preparedness for resuscitation in cases of anaphylaxis; postoperative patient monitoring to detect potential delayed AR; documentation of all AR for future reference. The findings of this study may be applied in clinical practice to mitigate the risks of AR associated with anaesthetic use during surgical interventions.
  • Functional Impact of MRGPRX2 Single-Nucleotide Polymorphisms on Drug-Induced Cellular Responses In Vitro. [Journal Article]
    Front Biosci (Landmark Ed). 2026 May 21; 31(5):51779.Dziadowiec A, Kwitniewski M, … Porebski GFB
  • CONCLUSIONS: Our findings indicate that under the investigated experimental conditions with ciprofloxacin, atracurium, and vancomycin: (1) N62S-transfected RBL-2H3 cells did not exhibit enhanced responses to the tested drug ligands; (2) the W248L variant exhibited the predicted loss-of-function phenotype, suggesting that in silico modeling may help assess the pathogenicity of specific MRGPRX2 variants; and (3) the remaining variants showed only partial concordance with previously published data, possibly reflecting differences in experimental design or assay conditions and highlighting the need for replication studies.
  • Current status of neuromuscular reversal and neuromuscular monitoring in China: a cross-sectional survey. [Journal Article]
    BMC Anesthesiol. 2026 May 25; 26(1).Tao JC, Zhou XY, … Yao YYBA
  • CONCLUSIONS: Our findings reveal substantial gaps in adherence to evidence-based practices for managing rNMB in China, particularly concerning the underutilization of quantitative monitoring and sugammadex. Systemic interventions to improve equipment accessibility, drug availability, and targeted education are crucial to enhance patient safety. Policy-driven resource allocation and standardized training programs are recommended to bridge the gap between evidence and practice.
  • Association between muscle relaxant dosage and recovery in pediatric otolaryngological surgery: A retrospective cohort study. [Journal Article]
    PLoS One. 2026; 21(4):e0346355.Tan J, Liu YPlos
  • CONCLUSIONS: Despite the absence of pharmacological reversal, no clinical manifestations of residual neuromuscular blockade-including hypoxemia, reintubation, or severe emergence agitation-were observed in any group.Notably, rocuronium 0.6 mg/kg exhibited rapid onset, superior intubation conditions, and hemodynamic stability; extubation times and emergence quality were comparable among all groups receiving a single intubating dose of 1-1.5 × ED95 of a neuromuscular blocking agent under the same intravenous-inhalation combined anesthesia.