- Surgery for Acute Type A Aortic Dissection in Patients Aged ≥75 Years: Six-Month Outcomes and Predictors of Mortality. [Journal Article]J Cardiothorac Vasc Anesth. 2026 Sep 08. [Online ahead of print]JC
- Publisher Full Text (DOI)
- Efficacy and tolerability of targeted lipoprotein(a)-lowering therapies: A systematic review. [Review]J Clin Lipidol. 2026 Aug 26. [Online ahead of print]JC
- CONCLUSIONS: Emerging Lp(a)-targeted therapies achieve significant reductions in circulating Lp(a) concentrations and represent a promising strategy for addressing residual cardiovascular risk associated with elevated Lp(a). Ongoing large-scale cardiovascular outcome trials will determine whether pharmacologic lowering of Lp(a) translates into reductions in cardiovascular events.
- Publisher Full Text (DOI)
- Pyelolymphatic backflow demonstrated on computed tomography urography in acute ureteric obstruction. [Case Reports]BMJ Case Rep. 2026 Oct 06; 19(10).BC
- A man in his early 40s presented with acute right flank pain, vomiting and dysuria. Ultrasonography demonstrated an obstructing right upper ureteric calculus with a contralateral renal calculus. CT urography revealed fine, serpiginous contrast-opacified tubular channels extending from the right renal pelvis into the retroperitoneum without evidence of urinoma. Delayed excretory phase imaging demo…
- Publisher Full Text (DOI)
- Sex Specific Associations between Visceral Adiposity and Aneurysm Formation: A New Piece of the Abdominal Aortic Aneurysm Puzzle. [Journal Article]Eur J Vasc Endovasc Surg. 2026 Oct 06. [Online ahead of print]EJ
- Publisher Full Text (DOI)
- Clinical Messages for Fenestrated Endovascular Aortic Repair from the GLOBALSTAR Registry: Outcomes in Salvage Fenestrated Endovascular Aneurysm Repair, Women, and Octogenarians. [Journal Article]Eur J Vasc Endovasc Surg. 2026 Oct 06. [Online ahead of print]EJ
- CONCLUSIONS: This study generated the following hypotheses: higher rates of re-intervention and graft related endoleak for salvage FEVAR may justify a FEVAR first strategy in appropriate cases, to achieve durable repair. Significantly worse peri-operative outcomes for women require further evaluation and may require changes in pre-operative pathways and case selection. Advanced age alone may not be a strong contraindication to FEVAR and effective case selection may yield acceptable outcomes for octogenarians. This study is limited by its retrospective design but is valuable in terms of its large real world cohort with extended follow up. The results highlight the need for dedicated prospective studies for the three subgroups, to elucidate mechanistic determinants.
- Publisher Full Text (DOI)
- Development and Internal Validation of the Si-AAA Prognostic Score for Five-Year Overall Survival after Endovascular Aneurysm Repair in Patients with Asymptomatic Abdominal Aortic Aneurysm. [Journal Article]Ann Vasc Surg. 2026 Oct 06. [Online ahead of print]AV
- CONCLUSIONS: A simple prognostic scoring system incorporating age, chronic obstructive pulmonary disease, unfit status, serum albumin, and aneurysm diameter demonstrated acceptable discrimination and good calibration for predicting 5-year overall survival after endovascular aneurysm repair. This tool may assist in risk stratification and long-term clinical decision-making. As this score was derived and internally validated in a single-center cohort, external validation in independent cohorts is required before routine clinical implementation.
- Publisher Full Text (DOI)
- Sex-based differences in mortality and prognostic factors for infective endocarditis: insights from a retrospective cohort of 519 patients. [Journal Article]Am Heart J. 2026 Oct 06; :107621. [Online ahead of print]AH
- CONCLUSIONS: Although overall mortality was similar between sexes, male patients and female patients with IE appeared to show different prognostic profiles in this single-center cohort. These preliminary, hypothesis-generating findings suggest that some established risk factors may largely reflect male data, emphasizing the need for larger, multicenter studies to confirm sex-specific determinants and improve individualized management.
- Publisher Full Text (DOI)
- Feasibility and safety of oral propranolol for heart rate control in pre-TAVI cardiac CT in severe aortic stenosis: A prospective study. [Journal Article]Rev Port Cardiol. 2026 Oct 06. [Online ahead of print]RP
- CONCLUSIONS: In selected patients with severe AS undergoing pre-TAVI CCTA, oral propranolol was associated with significant within-group HR reduction and no major adverse events. However, target HR achievement was similar between groups, and this comparison is limited by non-randomized treatment allocation and baseline differences. These findings support the feasibility and preliminary safety of propranolol, while further studies are needed to establish its efficacy and impact on image quality.
- Publisher Full Text (DOI)
- The deubiquitinase OTUD6B regulates cardiac hypertrophy by stabilizing TNF receptor associated factor 2. [Journal Article]Life Sci. 2026 Oct 06; :124722. [Online ahead of print]LS
- CONCLUSIONS: These findings suggest that OTUD6B positively regulates cardiac hypertrophy by stabilizing TRAF2 and identify OTUD6B as a target for hypertrophic therapy.
- Publisher Full Text (DOI)
- Thrombospondin-1 and Thrombospondin-2 are associated with biatrial fibrotic remodeling in human valvular heart disease. [Journal Article]Adv Med Sci. 2026 Oct 06. [Online ahead of print]AM
- CONCLUSIONS: Atrial TSPs expression was associated with fibrotic and inflammatory remodeling in valvular heart disease. Differences between transcript and protein findings and the use of pooled preparations warrant cautious interpretation. These observational findings require validation in independent cohorts and do not establish causality.
- Publisher Full Text (DOI)
- Clostridium septicum Aortitis and Mediastinitis Complicating Perforated Appendicitis in a Patient with Chronic Myelomonocytic Leukemia: A Case Report. [Case Reports]J Infect Chemother. 2026 Oct 06; :103098. [Online ahead of print]JI
- Clostridium septicum is an aerotolerant anaerobe classically linked to occult colorectal malignancy and hematologic disease, and a rare but frequently fatal cause of nontraumatic infective aortitis; it also causes gas gangrene, osteomyelitis and spondylodiscitis. Survival depends on radical surgical debridement, as antibiotics alone are almost uniformly fatal. We describe a 71-year-old man with u…
- Publisher Full Text (DOI)
- Patient-Surgeon Sex Concordance Affects Coronary Artery Bypass Grafting Outcomes. [Journal Article]J Thorac Cardiovasc Surg. 2026 Oct 06. [Online ahead of print]JT
- CONCLUSIONS: Female surgeons performed CABG on patients with higher comorbidity burden than male surgeons. While female patients had lower 30-day mortality with male surgeons, survival curves crossed at 90-days, after which survival was superior with female surgeons.
- Publisher Full Text (DOI)
- Early outcomes of the Octapro balloon-expandable transcatheter heart valve in an unrestricted cohort of patients with aortic valve stenosis: the MyPro registry. [Journal Article]Int J Cardiol. 2026 Oct 06; :134967. [Online ahead of print]IJ
- CONCLUSIONS: In this real-world registry, the Octapro THV demonstrated high procedural success, favourable early clinical outcomes, and excellent haemodynamic performance. Implantation depth and baseline RBBB were independent predictors of PPI, supporting optimization of implantation technique to mitigate conduction disturbances.
- Publisher Full Text (DOI)
- Timing of revascularisation in patients undergoing high-risk percutaneous coronary intervention and Transcatheter aortic valve implantation: insights from the ASCoP registry. [Journal Article]Int J Cardiol. 2026 Oct 06; :134968. [Online ahead of print]IJ
- CONCLUSIONS: In this high-risk TAVI cohort, the strategy of staging high-risk PCI after TAVI was associated with an increased risk of adverse events at 1-year.
- Publisher Full Text (DOI)
- Central aortic pressure and LV remodeling after surgical versus transcatheter repair of coarctation of aorta: Prospective data from the MACHD-biobank. [Journal Article]Int J Cardiol. 2026 Oct 06; :134963. [Online ahead of print]IJ
- CONCLUSIONS: Further studies are required to determine whether these observed differences central aortic hemodynamics and LV remodeling translate to differences in outcomes. There is also a need for a new paradigm for detection and management of central aortic hypertension in repaired COA.
- Publisher Full Text (DOI)