<?xml version="1.0" encoding="UTF-8"?><rss version="2.0"><channel><title>memantine</title><link>http://www.unboundmedicine.com/medline/ebm/research/memantine</link><description>Unbound MEDLINE is a service provided by Unbound Medicine, Inc. that includes data and services from the U.S. National Library of Medicine's MEDLINE® and PubMed® databases.</description><language>en-us</language><copyright>Unbound Medicine, Inc.</copyright><item><title>GluN2B subunit-containing NMDA receptor antagonists prevent A{beta}-mediated synaptic plasticity disruption in vivo.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19918059/full_citation/GluN2B_subunit_containing_NMDA_receptor_antagonists_prevent_A{beta}_mediated_synaptic_plasticity_disruption_in_vivo_</link><description>Hu NW, Klyubin I, Anwy R, et al. <br/><span class="title">GluN2B subunit-containing NMDA receptor antagonists prevent A{beta}-mediated synaptic plasticity disruption in vivo. [JOURNAL ARTICLE]</span><br/><span class="source" title="Proceedings of the National Academy of Sciences of the United States of America">Proc Natl Acad Sci U S A 2009 Nov 16.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19918059/abstract/GluN2B_subunit_containing_NMDA_receptor_antagonists_prevent_A{beta}_mediated_synaptic_plasticity_disruption_in_vivo_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19918059/full_citation/GluN2B_subunit_containing_NMDA_receptor_antagonists_prevent_A{beta}_mediated_synaptic_plasticity_disruption_in_vivo_">Full Citation</a> | <a href="http://www.pnas.org/cgi/pmidlookup%3fview=long%26amp;pmid=19918059">Publisher Full Text</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19918059/GluN2B_subunit_containing_NMDA_receptor_antagonists_prevent_A{beta}_mediated_synaptic_plasticity_disruption_in_vivo_">Find Related Articles</a> </description></item><item><title>Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19915593/full_citation/Balance_between_synaptic_versus_extrasynaptic_NMDA_receptor_activity_influences_inclusions_and_neurotoxicity_of_mutant_huntingtin_</link><description>Okamoto SI, Pouladi MA, Talantova M, et al. <br/><span class="title">Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin. [JOURNAL ARTICLE]</span><br/><span class="source" title="Nature medicine">Nat Med 2009 Nov 15.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19915593/abstract/Balance_between_synaptic_versus_extrasynaptic_NMDA_receptor_activity_influences_inclusions_and_neurotoxicity_of_mutant_huntingtin_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19915593/full_citation/Balance_between_synaptic_versus_extrasynaptic_NMDA_receptor_activity_influences_inclusions_and_neurotoxicity_of_mutant_huntingtin_">Full Citation</a> | <a href="http://dx.doi.org/10.1038/nm.2056">Publisher Full Text</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19915593/Balance_between_synaptic_versus_extrasynaptic_NMDA_receptor_activity_influences_inclusions_and_neurotoxicity_of_mutant_huntingtin_">Find Related Articles</a> </description></item><item><title>Improvement of negative and positive symptoms in treatment-refractory schizophrenia: a double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19906345/full_citation/Improvement_of_negative_and_positive_symptoms_in_treatment_refractory_schizophrenia:_a_double_blind_randomized_placebo_controlled_trial_with_memantine_as_add_on_therapy_to_clozapine_</link><description>de Lucena D, Fernandes BS, Berk M, et al. <br/><span class="title">Improvement of negative and positive symptoms in treatment-refractory schizophrenia: a double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine. [Journal Article, Research Support, Non-U.S. Gov't]</span><br/><span class="source" title="The Journal of clinical psychiatry">J Clin Psychiatry 2009 Oct; 70(10):1416-23.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19906345/abstract/Improvement_of_negative_and_positive_symptoms_in_treatment_refractory_schizophrenia:_a_double_blind_randomized_placebo_controlled_trial_with_memantine_as_add_on_therapy_to_clozapine_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19906345/full_citation/Improvement_of_negative_and_positive_symptoms_in_treatment_refractory_schizophrenia:_a_double_blind_randomized_placebo_controlled_trial_with_memantine_as_add_on_therapy_to_clozapine_">Full Citation</a> | <a href="http://article.psychiatrist.com/%3fContentType=START%26amp;ID=10006519">Publisher Full Text</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19906345/Improvement_of_negative_and_positive_symptoms_in_treatment_refractory_schizophrenia:_a_double_blind_randomized_placebo_controlled_trial_with_memantine_as_add_on_therapy_to_clozapine_">Find Related Articles</a> </description></item><item><title>Effects of Glucocorticoids on Mood, Memory, and the Hippocampus.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19906231/full_citation/Effects_of_Glucocorticoids_on_Mood_Memory_and_the_Hippocampus_</link><description>Brown ES <br/><span class="title">Effects of Glucocorticoids on Mood, Memory, and the Hippocampus. [JOURNAL ARTICLE]</span><br/><span class="source" title="Annals of the New York Academy of Sciences">Ann N Y Acad Sci 2009 Oct; 1179(1Glucocorticoids and Mood Clinical Manifestations, Risk Factors, and Molecular Mechanisms):41-55.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19906231/abstract/Effects_of_Glucocorticoids_on_Mood_Memory_and_the_Hippocampus_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19906231/full_citation/Effects_of_Glucocorticoids_on_Mood_Memory_and_the_Hippocampus_">Full Citation</a></description></item><item><title>Anti-apoptotic effect of memantine against staurosporine- and low-potassium-induced cell death in cerebellar granule cells: a development-dependent effect.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19904005/full_citation/Anti_apoptotic_effect_of_memantine_against_staurosporine__and_low_potassium_induced_cell_death_in_cerebellar_granule_cells:_a_development_dependent_effect_</link><description>Jantas D, Lasoń W <br/><span class="title">Anti-apoptotic effect of memantine against staurosporine- and low-potassium-induced cell death in cerebellar granule cells: a development-dependent effect. [Journal Article, Research Support, Non-U.S. Gov't]</span><br/><span class="source" title="Pharmacological reports : PR">Pharmacol Rep 2009 Sep-Oct; 61(5):827-937.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19904005/abstract/Anti_apoptotic_effect_of_memantine_against_staurosporine__and_low_potassium_induced_cell_death_in_cerebellar_granule_cells:_a_development_dependent_effect_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19904005/full_citation/Anti_apoptotic_effect_of_memantine_against_staurosporine__and_low_potassium_induced_cell_death_in_cerebellar_granule_cells:_a_development_dependent_effect_">Full Citation</a> | <a href="http://www.if-pan.krakow.pl/pjp/pdf/2009/5_827.pdf">Publisher Full Text</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19904005/Anti_apoptotic_effect_of_memantine_against_staurosporine__and_low_potassium_induced_cell_death_in_cerebellar_granule_cells:_a_development_dependent_effect_">Find Related Articles</a> </description></item><item><title>Effects of memantine on latent inhibition of active avoidance in wistar rats.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19902058/full_citation/Effects_of_memantine_on_latent_inhibition_of_active_avoidance_in_wistar_rats_</link><description>Loskutova LV, Kostjunina NV <br/><span class="title">Effects of memantine on latent inhibition of active avoidance in wistar rats. [Journal Article]</span><br/><span class="source" title="Bulletin of experimental biology and medicine">Bull Exp Biol Med 2009 Jun; 147(6):691-4.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19902058/abstract/Effects_of_memantine_on_latent_inhibition_of_active_avoidance_in_wistar_rats_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19902058/full_citation/Effects_of_memantine_on_latent_inhibition_of_active_avoidance_in_wistar_rats_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19902058/Effects_of_memantine_on_latent_inhibition_of_active_avoidance_in_wistar_rats_">Find Related Articles</a> </description></item><item><title>Alzheimer's disease: Seeing the signs early.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19900220/full_citation/Alzheimer's_disease:_Seeing_the_signs_early_</link><description>Leifer BP <br/><span class="title">Alzheimer's disease: Seeing the signs early. [Journal Article, Research Support, Non-U.S. Gov't]</span><br/><span class="source" title="Journal of the American Academy of Nurse Practitioners">J Am Acad Nurse Pract 2009 Nov; 21(11):588-95.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19900220/abstract/Alzheimer's_disease:_Seeing_the_signs_early_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19900220/full_citation/Alzheimer's_disease:_Seeing_the_signs_early_">Full Citation</a></description></item><item><title>Critical appraisal of the long-term impact of memantine in treatment of moderate to severe Alzheimer's disease.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19898670/full_citation/Critical_appraisal_of_the_long_term_impact_of_memantine_in_treatment_of_moderate_to_severe_Alzheimer's_disease_</link><description>Puangthong U, Hsiung GY <br/><span class="title">Critical appraisal of the long-term impact of memantine in treatment of moderate to severe Alzheimer's disease. [Journal Article]</span><br/><span class="source" title="Neuropsychiatric disease and treatment">Neuropsychiatr Dis Treat 2009.:553-61.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19898670/abstract/Critical_appraisal_of_the_long_term_impact_of_memantine_in_treatment_of_moderate_to_severe_Alzheimer's_disease_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19898670/full_citation/Critical_appraisal_of_the_long_term_impact_of_memantine_in_treatment_of_moderate_to_severe_Alzheimer's_disease_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19898670/Critical_appraisal_of_the_long_term_impact_of_memantine_in_treatment_of_moderate_to_severe_Alzheimer's_disease_">Find Related Articles</a> </description></item><item><title>Involvement of nicotinic receptors in methamphetamine- and MDMA-induced neurotoxicity: pharmacological implications.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19897077/full_citation/Involvement_of_nicotinic_receptors_in_methamphetamine__and_MDMA_induced_neurotoxicity:_pharmacological_implications_</link><description>Escubedo E, Camarasa J, Chipana C, et al. <br/><span class="title">Involvement of nicotinic receptors in methamphetamine- and MDMA-induced neurotoxicity: pharmacological implications. [Journal Article]</span><br/><span class="source" title="International review of neurobiology">Int Rev Neurobiol 2009.:121-66.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19897077/abstract/Involvement_of_nicotinic_receptors_in_methamphetamine__and_MDMA_induced_neurotoxicity:_pharmacological_implications_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19897077/full_citation/Involvement_of_nicotinic_receptors_in_methamphetamine__and_MDMA_induced_neurotoxicity:_pharmacological_implications_">Full Citation</a></description></item><item><title>Can we do better in developing new drugs for Alzheimer's disease?</title><link>http://www.unboundmedicine.com/medline/ebm/record/19896588/full_citation/Can_we_do_better_in_developing_new_drugs_for_Alzheimer's_disease</link><description>Gauthier S, Scheltens P <br/><span class="title">Can we do better in developing new drugs for Alzheimer's disease? 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