<?xml version="1.0" encoding="UTF-8"?><rss version="2.0"><channel><title>nilotinib</title><link>http://www.unboundmedicine.com/medline/ebm/research/nilotinib</link><description>Unbound MEDLINE is a service provided by Unbound Medicine, Inc. that includes data and services from the U.S. National Library of Medicine's MEDLINE® and PubMed® databases.</description><language>en-us</language><copyright>Unbound Medicine, Inc.</copyright><item><title>Clinical Pharmacokinetics of the BCR-ABL Tyrosine Kinase Inhibitor Nilotinib.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19924121/full_citation/Clinical_Pharmacokinetics_of_the_BCR_ABL_Tyrosine_Kinase_Inhibitor_Nilotinib_</link><description>Tanaka C, Yin OQ, Sethuraman V, et al. <br/><span class="title">Clinical Pharmacokinetics of the BCR-ABL Tyrosine Kinase Inhibitor Nilotinib. [JOURNAL ARTICLE]</span><br/><span class="source" title="Clinical pharmacology and therapeutics">Clin Pharmacol Ther 2009 Nov 18.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19924121/abstract/Clinical_Pharmacokinetics_of_the_BCR_ABL_Tyrosine_Kinase_Inhibitor_Nilotinib_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19924121/full_citation/Clinical_Pharmacokinetics_of_the_BCR_ABL_Tyrosine_Kinase_Inhibitor_Nilotinib_">Full Citation</a> | <a href="http://linkinghub.elsevier.com/retrieve/pii/clpt2009208 http://dx.doi.org/10.1038/clpt.2009.208">Publisher Full Text</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19924121/Clinical_Pharmacokinetics_of_the_BCR_ABL_Tyrosine_Kinase_Inhibitor_Nilotinib_">Find Related Articles</a> </description></item><item><title>Extended kinase profile and properties of the protein kinase inhibitor Nilotinib.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19922818/full_citation/Extended_kinase_profile_and_properties_of_the_protein_kinase_inhibitor_Nilotinib_</link><description>Manley PW, Drueckes P, Fendrich G, et al. <br/><span class="title">Extended kinase profile and properties of the protein kinase inhibitor Nilotinib. [JOURNAL ARTICLE]</span><br/><span class="source" title="Biochimica et biophysica acta">Biochim Biophys Acta 2009 Nov 13.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19922818/abstract/Extended_kinase_profile_and_properties_of_the_protein_kinase_inhibitor_Nilotinib_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19922818/full_citation/Extended_kinase_profile_and_properties_of_the_protein_kinase_inhibitor_Nilotinib_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19922818/Extended_kinase_profile_and_properties_of_the_protein_kinase_inhibitor_Nilotinib_">Find Related Articles</a> </description></item><item><title>Nilotinib: optimal therapy for patients with chronic myeloid leukemia and resistance or intolerance to imatinib.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19920925/full_citation/Nilotinib:_optimal_therapy_for_patients_with_chronic_myeloid_leukemia_and_resistance_or_intolerance_to_imatinib_</link><description>Swords R, Mahalingam D, Padmanabhan S, et al. <br/><span class="title">Nilotinib: optimal therapy for patients with chronic myeloid leukemia and resistance or intolerance to imatinib. [JOURNAL ARTICLE]</span><br/><span class="source" title="Drug design, development and therapy">Drug Des Devel Ther 2009.:89-101.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19920925/abstract/Nilotinib:_optimal_therapy_for_patients_with_chronic_myeloid_leukemia_and_resistance_or_intolerance_to_imatinib_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19920925/full_citation/Nilotinib:_optimal_therapy_for_patients_with_chronic_myeloid_leukemia_and_resistance_or_intolerance_to_imatinib_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19920925/Nilotinib:_optimal_therapy_for_patients_with_chronic_myeloid_leukemia_and_resistance_or_intolerance_to_imatinib_">Find Related Articles</a> </description></item><item><title>Development and targeted use of nilotinib in chronic myeloid leukemia.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19920910/full_citation/Development_and_targeted_use_of_nilotinib_in_chronic_myeloid_leukemia_</link><description>Fava C, Kantarjian H, Cortes J, et al. <br/><span class="title">Development and targeted use of nilotinib in chronic myeloid leukemia. [JOURNAL ARTICLE]</span><br/><span class="source" title="Drug design, development and therapy">Drug Des Devel Ther 2009.:233-243.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19920910/abstract/Development_and_targeted_use_of_nilotinib_in_chronic_myeloid_leukemia_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19920910/full_citation/Development_and_targeted_use_of_nilotinib_in_chronic_myeloid_leukemia_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19920910/Development_and_targeted_use_of_nilotinib_in_chronic_myeloid_leukemia_">Find Related Articles</a> </description></item><item><title>Severe toxicity of skin rash, fever and diarrhea associated with imatinib: case report and review of skin toxicities associated with tyrosine kinase inhibitors.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19920908/full_citation/Severe_toxicity_of_skin_rash_fever_and_diarrhea_associated_with_imatinib:_case_report_and_review_of_skin_toxicities_associated_with_tyrosine_kinase_inhibitors_</link><description>Huang X, Patel S, Ahmed N, et al. <br/><span class="title">Severe toxicity of skin rash, fever and diarrhea associated with imatinib: case report and review of skin toxicities associated with tyrosine kinase inhibitors. [JOURNAL ARTICLE]</span><br/><span class="source" title="Drug design, development and therapy">Drug Des Devel Ther 2009.:215-219.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19920908/abstract/Severe_toxicity_of_skin_rash_fever_and_diarrhea_associated_with_imatinib:_case_report_and_review_of_skin_toxicities_associated_with_tyrosine_kinase_inhibitors_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19920908/full_citation/Severe_toxicity_of_skin_rash_fever_and_diarrhea_associated_with_imatinib:_case_report_and_review_of_skin_toxicities_associated_with_tyrosine_kinase_inhibitors_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19920908/Severe_toxicity_of_skin_rash_fever_and_diarrhea_associated_with_imatinib:_case_report_and_review_of_skin_toxicities_associated_with_tyrosine_kinase_inhibitors_">Find Related Articles</a> </description></item><item><title>The occurrence and management of fluid retention associated with TKI therapy in CML, with a focus on dasatinib.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19909541/full_citation/The_occurrence_and_management_of_fluid_retention_associated_with_TKI_therapy_in_CML_with_a_focus_on_dasatinib_</link><description>Masiello D, Gorospe G, Yang AS <br/><span class="title">The occurrence and management of fluid retention associated with TKI therapy in CML, with a focus on dasatinib. [JOURNAL ARTICLE]</span><br/><span class="source" title="Journal of hematology &amp; oncology">J Hematol Oncol 2009 Nov 12; 2(1):46.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19909541/abstract/The_occurrence_and_management_of_fluid_retention_associated_with_TKI_therapy_in_CML_with_a_focus_on_dasatinib_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19909541/full_citation/The_occurrence_and_management_of_fluid_retention_associated_with_TKI_therapy_in_CML_with_a_focus_on_dasatinib_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19909541/The_occurrence_and_management_of_fluid_retention_associated_with_TKI_therapy_in_CML_with_a_focus_on_dasatinib_">Find Related Articles</a> </description></item><item><title>High-performance liquid chromatography with solid-phase extraction for the quantitative determination of nilotinib in human plasma.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19904720/full_citation/High_performance_liquid_chromatography_with_solid_phase_extraction_for_the_quantitative_determination_of_nilotinib_in_human_plasma_</link><description>Miura M, Takahashi N, Sawada KI <br/><span class="title">High-performance liquid chromatography with solid-phase extraction for the quantitative determination of nilotinib in human plasma. [JOURNAL ARTICLE]</span><br/><span class="source" title="Biomedical chromatography : BMC">Biomed Chromatogr 2009 Nov 10.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19904720/abstract/High_performance_liquid_chromatography_with_solid_phase_extraction_for_the_quantitative_determination_of_nilotinib_in_human_plasma_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19904720/full_citation/High_performance_liquid_chromatography_with_solid_phase_extraction_for_the_quantitative_determination_of_nilotinib_in_human_plasma_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19904720/High_performance_liquid_chromatography_with_solid_phase_extraction_for_the_quantitative_determination_of_nilotinib_in_human_plasma_">Find Related Articles</a> </description></item><item><title>Structural Analysis of DFG-in and DFG-out Dual Src-Abl Inhibitors Sharing a Common Vinyl Purine Template.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19895503/full_citation/Structural_Analysis_of_DFG_in_and_DFG_out_Dual_Src_Abl_Inhibitors_Sharing_a_Common_Vinyl_Purine_Template_</link><description>Zhou T, Commodore L, Huang WS, et al. <br/><span class="title">Structural Analysis of DFG-in and DFG-out Dual Src-Abl Inhibitors Sharing a Common Vinyl Purine Template. [JOURNAL ARTICLE]</span><br/><span class="source" title="Chemical biology &amp; drug design">Chem Biol Drug Des 2009 Nov 5.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19895503/abstract/Structural_Analysis_of_DFG_in_and_DFG_out_Dual_Src_Abl_Inhibitors_Sharing_a_Common_Vinyl_Purine_Template_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19895503/full_citation/Structural_Analysis_of_DFG_in_and_DFG_out_Dual_Src_Abl_Inhibitors_Sharing_a_Common_Vinyl_Purine_Template_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19895503/Structural_Analysis_of_DFG_in_and_DFG_out_Dual_Src_Abl_Inhibitors_Sharing_a_Common_Vinyl_Purine_Template_">Find Related Articles</a> </description></item><item><title>A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19890374/full_citation/A_comprehensive_target_selectivity_survey_of_the_BCR_ABL_kinase_inhibitor_INNO_406_by_kinase_profiling_and_chemical_proteomics_in_chronic_myeloid_leukemia_cells_</link><description>Rix U, Remsing Rix LL, Terker AS, et al. <br/><span class="title">A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells. [JOURNAL ARTICLE]</span><br/><span class="source" title="Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K">Leukemia 2009 Nov 5.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19890374/abstract/A_comprehensive_target_selectivity_survey_of_the_BCR_ABL_kinase_inhibitor_INNO_406_by_kinase_profiling_and_chemical_proteomics_in_chronic_myeloid_leukemia_cells_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19890374/full_citation/A_comprehensive_target_selectivity_survey_of_the_BCR_ABL_kinase_inhibitor_INNO_406_by_kinase_profiling_and_chemical_proteomics_in_chronic_myeloid_leukemia_cells_">Full Citation</a></description></item><item><title>Overcoming resistance in chronic myelogenous leukemia.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19883308/full_citation/Overcoming_resistance_in_chronic_myelogenous_leukemia_</link><description>Cooper S, Giles FJ, Savona MR <br/><span class="title">Overcoming resistance in chronic myelogenous leukemia. [Journal Article]</span><br/><span class="source" title="Leukemia &amp; lymphoma">Leuk Lymphoma 2009 Nov; 50(11):1785-93.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19883308/abstract/Overcoming_resistance_in_chronic_myelogenous_leukemia_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19883308/full_citation/Overcoming_resistance_in_chronic_myelogenous_leukemia_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19883308/Overcoming_resistance_in_chronic_myelogenous_leukemia_">Find Related Articles</a> </description></item></channel></rss>