<?xml version="1.0" encoding="UTF-8"?><rss version="2.0"><channel><title>tacrine</title><link>http://www.unboundmedicine.com/medline/ebm/research/tacrine</link><description>Unbound MEDLINE is a service provided by Unbound Medicine, Inc. that includes data and services from the U.S. National Library of Medicine's MEDLINE® and PubMed® databases.</description><language>en-us</language><copyright>Unbound Medicine, Inc.</copyright><item><title>Chromone glycosides and hepatoprotective constituents of Hypericum erectum.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19898802/full_citation/Chromone_glycosides_and_hepatoprotective_constituents_of_Hypericum_erectum_</link><description>An RB, Jeong GS, Beom JS, et al. <br/><span class="title">Chromone glycosides and hepatoprotective constituents of Hypericum erectum. [Journal Article]</span><br/><span class="source" title="Archives of pharmacal research">Arch Pharm Res 2009 Oct; 32(10):1393-7.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19898802/abstract/Chromone_glycosides_and_hepatoprotective_constituents_of_Hypericum_erectum_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19898802/full_citation/Chromone_glycosides_and_hepatoprotective_constituents_of_Hypericum_erectum_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19898802/Chromone_glycosides_and_hepatoprotective_constituents_of_Hypericum_erectum_">Find Related Articles</a> </description></item><item><title>Can we do better in developing new drugs for Alzheimer's disease?</title><link>http://www.unboundmedicine.com/medline/ebm/record/19896588/full_citation/Can_we_do_better_in_developing_new_drugs_for_Alzheimer's_disease</link><description>Gauthier S, Scheltens P <br/><span class="title">Can we do better in developing new drugs for Alzheimer's disease? [Editorial]</span><br/><span class="source" title="Alzheimer's &amp; dementia : the journal of the Alzheimer's Association">Alzheimers Dement 2009 Nov; 5(6):489-91.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19896588/abstract/Can_we_do_better_in_developing_new_drugs_for_Alzheimer's_disease">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19896588/full_citation/Can_we_do_better_in_developing_new_drugs_for_Alzheimer's_disease">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19896588/Can_we_do_better_in_developing_new_drugs_for_Alzheimer's_disease">Find Related Articles</a> </description></item><item><title>Effects of Cholinesterase Inhibitors on the Activities and Protein Levels of Cholinesterases in the Cerebrospinal Fluid of Patients with Alzheimer's Disease: A Review of Recent Clinical Studies.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19860725/full_citation/Effects_of_Cholinesterase_Inhibitors_on_the_Activities_and_Protein_Levels_of_Cholinesterases_in_the_Cerebrospinal_Fluid_of_Patients_with_Alzheimer's_Disease:_A_Review_of_Recent_Clinical_Studies_</link><description>Darreh-Shori T, Soininen H <br/><span class="title">Effects of Cholinesterase Inhibitors on the Activities and Protein Levels of Cholinesterases in the Cerebrospinal Fluid of Patients with Alzheimer's Disease: A Review of Recent Clinical Studies. [JOURNAL ARTICLE]</span><br/><span class="source" title="Current Alzheimer research">Curr Alzheimer Res 2009 Sep 28.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19860725/abstract/Effects_of_Cholinesterase_Inhibitors_on_the_Activities_and_Protein_Levels_of_Cholinesterases_in_the_Cerebrospinal_Fluid_of_Patients_with_Alzheimer's_Disease:_A_Review_of_Recent_Clinical_Studies_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19860725/full_citation/Effects_of_Cholinesterase_Inhibitors_on_the_Activities_and_Protein_Levels_of_Cholinesterases_in_the_Cerebrospinal_Fluid_of_Patients_with_Alzheimer's_Disease:_A_Review_of_Recent_Clinical_Studies_">Full Citation</a></description></item><item><title>A New Tacrine-Melatonin Hybrid Reduces Amyloid Burden and Behavioral Deficits in a Mouse Model of Alzheimer's Disease.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19774434/full_citation/A_New_Tacrine_Melatonin_Hybrid_Reduces_Amyloid_Burden_and_Behavioral_Deficits_in_a_Mouse_Model_of_Alzheimer's_Disease_</link><description>Spuch C, Antequera D, Isabel Fernandez-Bachiller M, et al. <br/><span class="title">A New Tacrine-Melatonin Hybrid Reduces Amyloid Burden and Behavioral Deficits in a Mouse Model of Alzheimer's Disease. [JOURNAL ARTICLE]</span><br/><span class="source" title="Neurotoxicity research">Neurotox Res 2009 Sep 23.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19774434/abstract/A_New_Tacrine_Melatonin_Hybrid_Reduces_Amyloid_Burden_and_Behavioral_Deficits_in_a_Mouse_Model_of_Alzheimer's_Disease_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19774434/full_citation/A_New_Tacrine_Melatonin_Hybrid_Reduces_Amyloid_Burden_and_Behavioral_Deficits_in_a_Mouse_Model_of_Alzheimer's_Disease_">Full Citation</a></description></item><item><title>Synthetic and Natural Compounds that Interact with Human Cytochrome P450 1A2 and Implications in Drug Development.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19754423/full_citation/Synthetic_and_Natural_Compounds_that_Interact_with_Human_Cytochrome_P450_1A2_and_Implications_in_Drug_Development_</link><description>Wang B, Zhou SF <br/><span class="title">Synthetic and Natural Compounds that Interact with Human Cytochrome P450 1A2 and Implications in Drug Development. [JOURNAL ARTICLE]</span><br/><span class="source" title="Current medicinal chemistry">Curr Med Chem 2009 Sep 16.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19754423/abstract/Synthetic_and_Natural_Compounds_that_Interact_with_Human_Cytochrome_P450_1A2_and_Implications_in_Drug_Development_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19754423/full_citation/Synthetic_and_Natural_Compounds_that_Interact_with_Human_Cytochrome_P450_1A2_and_Implications_in_Drug_Development_">Full Citation</a></description></item><item><title>Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19720731/full_citation/Evaluation_of_the_potential_for_drug_induced_liver_injury_based_on_in_vitro_covalent_binding_to_human_liver_proteins_</link><description>Usui T, Mise M, Hashizume T, et al. <br/><span class="title">Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins. [JOURNAL ARTICLE]</span><br/><span class="source" title="Drug metabolism and disposition: the biological fate of chemicals">Drug Metab Dispos 2009 Aug 31.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19720731/abstract/Evaluation_of_the_potential_for_drug_induced_liver_injury_based_on_in_vitro_covalent_binding_to_human_liver_proteins_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19720731/full_citation/Evaluation_of_the_potential_for_drug_induced_liver_injury_based_on_in_vitro_covalent_binding_to_human_liver_proteins_">Full Citation</a></description></item><item><title>Mechanisms of Neuroprotective Effects of Nicotine and Acetylcholinesterase Inhibitors: Role of alpha4 and alpha7 Receptors in Neuroprotection.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19714494/full_citation/Mechanisms_of_Neuroprotective_Effects_of_Nicotine_and_Acetylcholinesterase_Inhibitors:_Role_of_alpha4_and_alpha7_Receptors_in_Neuroprotection_</link><description>Akaike A, Takada-Takatori Y, Kume T, et al. <br/><span class="title">Mechanisms of Neuroprotective Effects of Nicotine and Acetylcholinesterase Inhibitors: Role of alpha4 and alpha7 Receptors in Neuroprotection. [JOURNAL ARTICLE]</span><br/><span class="source" title="Journal of molecular neuroscience : MN">J Mol Neurosci 2009 Aug 28.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19714494/abstract/Mechanisms_of_Neuroprotective_Effects_of_Nicotine_and_Acetylcholinesterase_Inhibitors:_Role_of_alpha4_and_alpha7_Receptors_in_Neuroprotection_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19714494/full_citation/Mechanisms_of_Neuroprotective_Effects_of_Nicotine_and_Acetylcholinesterase_Inhibitors:_Role_of_alpha4_and_alpha7_Receptors_in_Neuroprotection_">Full Citation</a></description></item><item><title>Insights into the Structure, Function, and Regulation of Human Cytochrome P450 1A2.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19702530/full_citation/Insights_into_the_Structure_Function_and_Regulation_of_Human_Cytochrome_P450_1A2_</link><description>Zhou SF, Chan E, Zhou ZW, et al. <br/><span class="title">Insights into the Structure, Function, and Regulation of Human Cytochrome P450 1A2. [JOURNAL ARTICLE]</span><br/><span class="source" title="Current drug metabolism">Curr Drug Metab 2009 Sep 1.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19702530/abstract/Insights_into_the_Structure_Function_and_Regulation_of_Human_Cytochrome_P450_1A2_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19702530/full_citation/Insights_into_the_Structure_Function_and_Regulation_of_Human_Cytochrome_P450_1A2_">Full Citation</a> | <a rel="nofollow" href="http://www.unboundmedicine.com/medline/ebm/related/19702530/Insights_into_the_Structure_Function_and_Regulation_of_Human_Cytochrome_P450_1A2_">Find Related Articles</a> </description></item><item><title>Electrophoretically mediated microanalysis technique as a tool for the rapid screening of novel acetylcholinesterase inhibitors.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19702166/full_citation/Electrophoretically_mediated_microanalysis_technique_as_a_tool_for_the_rapid_screening_of_novel_acetylcholinesterase_inhibitors_</link><description>Bajda M, Wieckowska A, Malawska B <br/><span class="title">Electrophoretically mediated microanalysis technique as a tool for the rapid screening of novel acetylcholinesterase inhibitors. [Journal Article]</span><br/><span class="source" title="Acta poloniae pharmaceutica">Acta Pol Pharm 2009 Jul-Aug; 66(4):357-62.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19702166/abstract/Electrophoretically_mediated_microanalysis_technique_as_a_tool_for_the_rapid_screening_of_novel_acetylcholinesterase_inhibitors_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19702166/full_citation/Electrophoretically_mediated_microanalysis_technique_as_a_tool_for_the_rapid_screening_of_novel_acetylcholinesterase_inhibitors_">Full Citation</a></description></item><item><title>Long-lasting decreases in cocaine-reinforced behavior following treatment with the cholinesterase inhibitor tacrine in rats selectively bred for drug self-administration.</title><link>http://www.unboundmedicine.com/medline/ebm/record/19698738/full_citation/Long_lasting_decreases_in_cocaine_reinforced_behavior_following_treatment_with_the_cholinesterase_inhibitor_tacrine_in_rats_selectively_bred_for_drug_self_administration_</link><description>Grasing K, He S, Yang Y <br/><span class="title">Long-lasting decreases in cocaine-reinforced behavior following treatment with the cholinesterase inhibitor tacrine in rats selectively bred for drug self-administration. [JOURNAL ARTICLE]</span><br/><span class="source" title="Pharmacology, biochemistry, and behavior">Pharmacol Biochem Behav 2009 Aug 18.</span><br/> <a href="http://www.unboundmedicine.com/medline/ebm/record/19698738/abstract/Long_lasting_decreases_in_cocaine_reinforced_behavior_following_treatment_with_the_cholinesterase_inhibitor_tacrine_in_rats_selectively_bred_for_drug_self_administration_">Abstract</a> | <a href="http://www.unboundmedicine.com/medline/ebm/record/19698738/full_citation/Long_lasting_decreases_in_cocaine_reinforced_behavior_following_treatment_with_the_cholinesterase_inhibitor_tacrine_in_rats_selectively_bred_for_drug_self_administration_">Full Citation</a></description></item></channel></rss>