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(Current opinion in organ transplantation[TA]) articles in PubMed
949 results
  • Long-term effects of islet transplantation. [Journal Article]
  • Curr Opin Organ Transplant 2016; 21(5):497-502CO
  • Holmes-Walker DJ, Kay TW
  • CONCLUSIONS: Reversal of hypoglycemia unawareness and protection from severe hypoglycemia events are two of the main benefits of islet transplantation and they persist for the duration of graft function. Islet transplantation compares favorably with other therapies for those with hypoglycemia unawareness, although new technologies have not been tested head-to-head with transplantation. HLA sensitization increases with time after transplantation especially if immunosuppression is ceased and is a risk for those who may require future transplantation as well as being associated with loss of graft function.
  • Development and refinement of computer-assisted planning and execution system for use in face-jaw-teeth transplantation to improve skeletal and dento-occlusal outcomes. [Journal Article]
  • Curr Opin Organ Transplant 2016; 21(5):523-9CO
  • Hashemi S, Armand M, Gordon CR
  • CONCLUSIONS: A comprehensive CAPE system for use in FJTT was developed through a multicenter collaboration and refined using plastic models, live miniature swine surgery, and human cadaver models. The system marries preoperative surgical planning and intraoperative execution by allowing on-table navigation of the donor fragment relative to recipient cranium, and real-time reporting of patient's cephalometric measurements relative to a desired dental-skeletal outcome. FJTTs using live-animal and cadaveric models demonstrate the CAPE system to be accurate in navigation and beneficial in improving hybrid occlusion and other craniofacial outcomes. Future refinement of the CAPE system includes integration of more commonly performed orthognathic/maxillofacial procedures.
  • An integrated view of immune monitoring in vascularized composite allotransplantation. [Journal Article]
  • Curr Opin Organ Transplant 2016; 21(5):516-22CO
  • Sicard A, Kanitakis J, … Morelon E
  • CONCLUSIONS: Strategies that integrate both the current 'gold standards' of monitoring in VCA and a complementary multilayer immunological assessment are likely to provide the highest precision for the personalized determination of the recipients' immunological status. The objective is a tailored adaptation of immunosuppressive treatment.
  • Standardizing psychosocial assessment for vascularized composite allotransplantation. [Journal Article]
  • Curr Opin Organ Transplant 2016; 21(5):530-5CO
  • Jowsey-Gregoire S, Kumnig M
  • CONCLUSIONS: Although VCA is not a lifesaving procedure, as in solid organ transplantation, the following areas require assessment: psychiatric stability, history of chemical dependence, family support, adherence and understanding of transplantation. VCA requires the incorporation of a visible allograft, lengthy rehabilitation, occupational considerations, prosthetic use, possible screening for posttraumatic stress disorder related to injuries and phantom limb pain. Intense media interest may lead to distress. Development of an instrument to address these areas initially and over time to monitor for changes in QOL and training the psychosocial team is a priority.
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