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(Drug Dev Ind Pharm[TA]) articles in PubMed
3,105 results
  • Tear fluid-eye drops compatibility assessment using surface tension. [Journal Article]
  • Drug Dev Ind Pharm 2016 Sep 19; :1-21DD
  • Hotujac Grgurević M, Juretić M, … Pepić I
  • CONCLUSIONS: There are a number of quality requirements for the eye drops (e.g., tonicity, pH, viscosity, refractive index) that needs to comply with the physiological parameters of the eye surface. However, the adjustment of surface tension properties of the eye drops to the normal range of surface tension at the air/tear fluid interface (40-46 mN/m) has received rather less attention thus far. Yet, the surface tension at the air/tear fluid interface is of vital importance for the normal function of the eye surface.Our results provide a rationale for clinical studies aiming to assess the correlation between the eye drops surface tension and the tear film (in)stability.
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