Hospital formulary [journal]
- Pharmaceutical industry wins "round one" in protections against product liability claims. [Journal Article]
- Hosp Formul 1995 Apr; 30(4):238, 237.
- Safety, efficacy, and lipid profile of doxazosin at a VA medical center. [Journal Article]
- Hosp Formul 1995 Apr; 30(4):233-6.
The Veterans Administration Lakeside Medical Center (VALMC) is a 500-bed hospital located in downtown Chicago providing a broad scope of inpatient and outpatient medical services for more than 12,000 veterans. The VALMC Pharmacy and Therapeutics Committee requested a study to evaluate doxazosin mesylate (Cardura) to determine if this agent would be an acceptable alternative to other formulary agents. It appears that doxazosin provides several therapeutic advantages, including once-daily dosing, when compared with other more costly antihypertensive agents.
- A team approach to adverse drug reaction surveillance: success at a tertiary care hospital. [Journal Article]
- Hosp Formul 1995 Apr; 30(4):226-8, 231-2.
A retrospective adverse drug reaction (ADR) reporting system has been in place at Cedars-Sinai Medical Center for 7 years. Initially, the system identified 300 to 400 ADRs per year. After adding a checklist, that number increased to 750 to 850 per year, an ADR rate of about 2% of total patient admissions. To increase the ADR reporting rate, we initiated a concurrent surveillance program in conjunction with the retrospective system. In the first year of the program, the combined systems identified 1,174 ADRs. In addition, the ADR rate per 100 patient days increased to between 0.5 and 0.7, and the ADR per admission rate increased to 4%. As a result of the more effective ADR surveillance program, the P & T Committee has additional data from which to develop guidelines and educational programs to increase ADR awareness and prevention, and thus, to improve patient outcomes.
- The drive to reform the FDA gains momentum. [Journal Article]
- Hosp Formul 1995 Mar; 30(3):178, 177.
- Who should conduct outcomes research? [Journal Article]
- Hosp Formul 1995 Mar; 30(3):171-2.
- The changing relationship between health care professionals and the pharmaceutical industry. [Journal Article]
- Hosp Formul 1995 Mar; 30(3):161-5; discussion 163-9.
Although UCLA had established policies and procedures for visiting pharmaceutical representatives, changes in both the pharmaceutical business environment and in UCLA's physical environment mandated an update. To deal with the changes, a multidisciplinary team comprised of various departmental staff members met to develop a new vendor representative visitation policy that included the practice of drug sample distribution. More stringent registration requirements and shared responsibility for policy enforcement are the key elements of the new policy.
- Antibiotic therapeutic interchange program: six years of experience. [Journal Article]
- Hosp Formul 1995 Feb; 30(2):92-3, 97-8, 100 passim.
To assess the long-term impact of a therapeutic interchange program on the use of target antimicrobial drugs, we conducted a retrospective study of target drug utilization at our institution--a 1,000-bed Canadian tertiary care teaching hospital. Data were assessed to determine target drug utilization, incidence of therapeutic interchanges, and patient-target drug exposures. Results showed that the incidence of therapeutic interchanges per patient-target drug exposure decreased from a mean of 23% to 2%, resulting in a total net savings for the target drugs of approximately $1.07 million (Canadian) over 6 years. Prescriber acceptance and low manpower requirements combine to make this a useful method of altering prescribing patterns and reducing drug and drug delivery costs.
- Health issues on hold, but lurking behind GOP's Contract with America. [Journal Article]
- Hosp Formul 1995 Feb; 30(2):118, 117.
- How a CQI program improved aminoglycoside use in a community hospital. [Journal Article]
- Hosp Formul 1995 Feb; 30(2):114-6.
The P & T Committee of our institution, a 285-bed, non-tertiary care regional medical center, undertook a study to evaluate the use of the aminoglycoside amikacin sulfate (Amikin). Results of an initial DUE, a follow-up to an educational effort, and the estimated annual cost savings that could be achieved with appropriate prescribing of aminoglycosides are presented.
- Automation in pharmacy: two institutions' experiences with novel distribution systems. [Journal Article]
- Hosp Formul 1995 Feb; 30(2):106-13.
A computerized medication system, implemented at Rochester (MN) Methodist Hospital in 1987, has been adopted by the hospitals at the Mayo Medical Center, Rochester, MN. A key component of the medication system, which uses individualized patient medication envelopes, is the delivery of doses of medications to nursing units just before their administration time. The system has been shown to provide greater nursing support, increase patient safety by reducing medication errors, and decrease both full-time equivalent costs and operating costs. The immediate impact of the system has been to shift dose scheduling from a nursing to a pharmacy responsibility. At Duke University, an automated pharmacy system (APS) has been in operation since October 1993 and is used to dispense the majority of unit dose drugs. The APS provides up-to-the-minute information about the drugs that patients are receiving, which is used to fill each patient's unit dose drawer. It has not dispensed an incorrect drug since its installation and has allowed centralization of the unit dose cart system. Other benefits include decreased billing labor and increased drug usage reporting.