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(Journal of affective disorders[TA]) articles in PubMed
8,241 results
  • Trait-related alterations of N-acetylaspartate in euthymic bipolar patients: A longitudinal proton magnetic resonance spectroscopy study. [Journal Article]
  • J Affect Disord 2016 Sep 9; 206:315-320JA
  • Aydin B, Yurt A, … Yildiz A
  • CONCLUSIONS: of our study include a relatively low (1.5T) magnetic resonance field strength and variable drugs administered to achieve euthymia despite the best efforts to standardize the open fashion treatment.Our study contributes to the integrating models of trait-related metabolite alterations observed in euthymia since NAA is considered as a marker of neuronal viability and mitochondrial energy metabolism. In light of supporting and conflicting results reported previously, future studies with longitudinal designs and larger patient groups are warranted to better define both state- and trait-related cerebral metabolic alterations associated with BD pathophysiology.
  • Continuation phase intravenous ketamine in adults with treatment-resistant depression. [Journal Article]
  • J Affect Disord 2016 Sep 12; 206:300-304JA
  • Vande Voort JL, Morgan RJ, … Bobo WV
  • CONCLUSIONS: This was an uncontrolled feasibility study with a small sample size.The continuation-phase administration of ketamine at weekly intervals to patients with treatment-resistant depression who remitted during acute-phase ketamine treatment can extend the duration of depressive symptom remission. The antidepressive effect of ketamine persisted for several weeks after the end of continuation-phase treatment. Our results highlight the need for close monitoring of subjects who are at high baseline risk for suicide but do not respond clinically to ketamine. CLINICALTRIALS.
  • Rates and characteristics of elderly suicide in China, 2013-14. [Journal Article]
  • J Affect Disord 2016 Sep 13; 206:273-279JA
  • Zhong BL, Chiu HF, Conwell Y
  • CONCLUSIONS: Information on means of ES are lacking in the data source.ESs disproportionately account for a large portion of China's current total suicides, and ESR, particularly in central rural OAs, is very high in China. Prevention of ES should be given priority as an important public health issue in China. Central rural OAs are key target population for current ES prevention.
  • Individual and area-level risk factors for suicidal ideation and attempt in people with severe depression. [Journal Article]
  • J Affect Disord 2016 Aug 22; 205:387-392JA
  • Werbeloff N, Markou M, … Osborn DP
  • CONCLUSIONS: Data were not collected specifically for research purposes and hence information on some potential confounders was not available. Additionally, information was restricted to individuals who accessed secondary mental health services in a defined catchment area and period. The study therefore does not take into account individuals who did not access mental health services.The variation in risk for suicidal ideation and attempt among severely depressed individuals is explained by differences in individual socio-demographic and clinical characteristics, most notably past psychiatric admission and substance misuse, and not by area-level measures.
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