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(Journal of clinical pathology[TA])
15,781 results
  • PIK3CA and AKT1 mutations in hidradenoma papilliferum. [Journal Article]
  • JCJ Clin Pathol 2016 Oct 14
  • Goto K, Maeda D, … Goto A
  • CONCLUSIONS: PIK3CA and AKT1 are frequently mutated in HP tumours (29% and 14%, respectively). PIK3CA/AKT1 pathway alterations in HP further support the hypothesis that HP is the vulvar (anogenital mammary-like gland) analogue of breast intraductal papilloma.
  • Benchmarking a large regional UK HER2 testing service against current practice guidelines. [Journal Article]
  • JCJ Clin Pathol 2016 Oct 5
  • Thomas J, Loane J, … Ferrigan L
  • CONCLUSIONS: Single counting of HER2 FISH supported by a second rapid screen is safe and practicable within strict parameters. Any assessment of proximity of scores in double-scored cases should take into account the HER2 copy number, with greater spreads experienced at higher copy numbers. Centralising HER2 testing in a regional centre allows detailed audit of the entire analytical process.
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