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(Theoretical biology medical modelling[TA]) articles in PubMed
533 results
  • Feed-forward neural network model for hunger and satiety related VAS score prediction. [Journal Article]
  • Theor Biol Med Model 2016; 13(1):17TB
  • Krishnan S, Hendriks HF, … de Graaf AA
  • CONCLUSIONS: From this application of artificial neural networks, one may conclude that neural network models are very suitable to describe situations where behavior is complex and incompletely understood. However, training data sets that fit the experimental conditions need to be available.
  • Random walk of passive tracers among randomly moving obstacles. [Journal Article]
  • Theor Biol Med Model 2016; 13:13TB
  • Gori M, Donato I, … Pettini M
  • CONCLUSIONS: The results reported here suggest that if a biomolecule, let us call it a test molecule, moves towards its target in the presence of other independently interacting molecules, its motion can be considerably slowed down.
  • The organelle of differentiation in embryos: the cell state splitter. [Review]
  • Theor Biol Med Model 2016; 13:11TB
  • Gordon NK, Gordon R
  • The cell state splitter is a membraneless organelle at the apical end of each epithelial cell in a developing embryo. It consists of a microfilament ring and an intermediate filament ring subtending ...
  • Modeling immune response and its effect on infectious disease outbreak dynamics. [Journal Article]
  • Theor Biol Med Model 2016; 13:10TB
  • Reyes-Silveyra J, Mikler AR
  • CONCLUSIONS: Our results suggest that it is essential for the public health establishment to increase their understanding of the characteristics of regional demographics that could impact the quality of the immune response of the individuals. The results indicate that it is necessary to further investigate mitigation strategies to limit the capacity to transmit the disease by individuals that spread the pathogen for extended periods of time. Ultimately, this study suggests that it is crucial for public health researchers to identify appropriate targeted vaccination regimes and to explore the link between PIR and outbreak dynamics to improve the monitoring and mitigating efforts of ongoing and future epidemics.
  • A physiologically-based flow network model for hepatic drug elimination III: 2D/3D DLA lobule models. [Journal Article]
  • Theor Biol Med Model 2016; 13:9TB
  • Rezania V, Coombe D, Tuszynski JA
  • CONCLUSIONS: Although, the individual producing ports respond differently, the average lobule production summed over all hepatic veins is more diffuse. Thus the net effect of all these variations makes the overall response smoother. We also show that, in 3D, the effect of zonation on drug production characteristics appears quite small. Our new biophysical structural analysis of a physiologically-based 3D lobule can therefore form the basis for a quantitative assessment of liver function and performance both in health and disease.
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