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Vestn Otorinolaringol [journal]
- [Cochlear implantation in the immunocompromised patients.] [JOURNAL ARTICLE]
- Vestn Otorinolaringol 2014; (2):93-94.
This paper reports a clinical case that gives evidence of the possibility of cochlear implantation after liver transplantation. Patient K. aged 3 years 10 months was admitted to the Russian Research and Practical Centre of Audiology and Hearing Rehabilitation with the diagnosis of type IB glycogenosis after maternal liver transplantation associated with chronic neutropenia, chronic cutaneous and mucosal infection, partial symptomatic partial epilepsy, retarded psycho-motor development, and complaints of the absence of auditory response. The audiological examination provided materials for the diagnosis of grade IV bilateral sensorineural hearing loss tending toward deafness. Cochlear implantation recommended to the patient was performed on February 20, 2013 using the HiRes 90 K implant with the HiFocus Helix electrode (Advanced Bionics, USA). The surgical intervention and the postoperative period passed without complications. The speech processor was activated one month after surgery. The results of surdopedagogical testing gave evidence of successful rehabilitation promising the further improvement. It is concluded that immunosuppressive therapy is not an absolute contraindication for cochlear implantation, but this procedure requires detailed examination and thorough preparation for the forthcoming surgery.
- [Johanson-Blizzard syndrome: the audiological features and results of cochlear implantation.] [JOURNAL ARTICLE]
- Vestn Otorinolaringol 2014; (2):90-92.
Johanson-Blizzard syndrome is a rare congenital autosomal recessive disease characterized by the association of congenital deficiency of the exocrine pancreatic function and multiple malformations. One of the most common manifestations of this pathology is sensorineural hearing loss of different severity and anomalous development of the inner ear. The case of cochlear implantation in the patient presenting with bilateral sensorineural deafness, congenital malformation of the inner ear, and stenosis of the internal auditory canal is reported.
- [The therapeutic modalities for the management of cough associated with acute respiratory viral infection used in the practical work of an otolaryngologist.] [JOURNAL ARTICLE]
- Vestn Otorinolaringol 2014; (2):86-89.
The objective of the present study was to evaluate the effectiveness ascoril therapy in comparison with the treatment using the mucoactive agent lazolvanom in the adult patients suffering from productive cough associated with acute viral respiratory infection. Patients and methods. The study included 120 patients suffering from productive cough associated with acute viral respiratory infection. They were divided into two groups. The patients comprising group 1 (n=6.) were treated with ascoril, those in group 2 (n=60) were given lasolvan. Results. The effectiveness of the treatment of cough in group 1 was found to be higher compared with that in group 2 (p<0.05); moreover, it was associated with better dynamics of certain indicators of the quality of life, such as the social activity level, vitality, and general health (p<0.05). The safety of the proposed treatment was confirmed by the absence of the adverse events throughout the entire treatment period.
- [Allergic rhinitis: allergist's point of view.] [JOURNAL ARTICLE]
- Vestn Otorinolaringol 2014; (2):82-85.
Allergic rhinitis is a serious medical and social problem associated with the continuously increasing morbidity level and imposing a high economic burden on the healthcare delivery system for the management of this condition. In accordance with the concept of "personalized medicine", the prescription of intranasal or oral antihistaminic agents, intranasal glucocorticosteroids and oral antagonists of antileukotrienic medicines as well as decongestants and therapeutic preparations of other classes for the treatment of allergic rhinitis should be well substantiated and based on an individual approach to a patient in every particular case.
- [The role of biofilms in pathogenesis of chronic bacterial rhinosinusitis.] [JOURNAL ARTICLE]
- Vestn Otorinolaringol 2014; (2):79-81.
The objective of the present work was to study the contribution of biofilms to the development of chronic bacterial rhinosinusitis. A total of 50 patients with this pathology were available for the examination. Mucosal swabs were taken from the middle nasal passages of all the patients to be used for the detection of biofilms by luminescence microscopy. The lactoferrine content in mucosal secretion from the nasal cavity was determined by an immunoenzymatic assay. Two groups of the patients presenting with bacterial rhinosinusitis were distinguished in the study of impression smears from nasal cavity mucosa by luminescence microscopy; one of them was comprised of biofilm-positive patients the other of biofilm-negative ones (56% and 44% respectively). The patients showing biofilms over nasal cavity mucosa had the lactoferrine content in mucosal secretion on the order of 0.0033±0.0008 mg/l compared with 0.0068±0.00075 mg/l in the biofilm-negative patients and 0.55±0.0005 mg/l in the healthy volunteers (controls). In other words, the biofilm-positive patients presenting with chronic bacterial rhinosinusitis had two times lower content of lactoferrine in mucosal secretion from the middle nasal passages than those in the biofilm negative group and 126 times lower content of lactoferrine than in the control group.
- [The effectiveness of a herbal preparation Tonsilgon N for the treatment of the children presenting with chronic adenoiditis.] [JOURNAL ARTICLE]
- Vestn Otorinolaringol 2014; (2):75-78.
The objective of the present study was to estimate the effectiveness of the herbal preparation tonsilgon N exhibiting the anti-inflammatory and immunostimulating properties for the treatment of the children presenting with pathology of a pharyngeal tonsil. A total of 62 children at the age varying from 3 to 11 years with chronic adenoiditis (CA) were available for the examination. The study group was comprised of 32 children, the control one included 30 patients. The study has demonstrated the improvement of daytime nasal breathing in the study group compared with the control patients by 15% on day 5, by 30% on day 7, and by 73% on day 9 after the onset of the treatment. The intensity of rhinorrhea in the children treated with the herbal preparation decreased sooner than in the control group. Nasal breathing at night improved as soon as day 5 after the onset of therapy. However, the difference between the treated and control children was statistically significant only on day 7 whereas night-time nasal breathing on day 9 improved in the study group by 1.4 times compared with the control one. It is concluded that the inclusion of therapy with tonsilgon N in the combined treatment of the children presenting with chronic adenoiditis increases its effectiveness and accelerates the process of reconvalescence. Tonsilgon N is a safe medication suitable for the prolonged application.
- [On the necessity of standardization of the objective methods for the study of the hearing function in the children presenting with acute inflammatory diseases of the middle ear at the level of the outpatient treatment.] [JOURNAL ARTICLE]
- Vestn Otorinolaringol 2014; (2):73-74.
The objective of the present study was to standardize the frequency of objective evaluation of the hearing function in the children presenting with acute inflammatory diseases of the middle ear at the level of the outpatient treatment. The studies carried out to this effect with the use of modern and readily available audiological method revealed functional disorders in the middle ear of more than 50% of the children suffering from acute non-perforative otitis even after the elimination of the clinical signs of inflammation. The complete restoration of the functional state of the middle ear was documented in all the patients following the rehabilitative treatment. The authors proposed the algorithm for the examination of the children presenting with acute inflammatory diseases of the middle ear with special reference to the optimal frequency of diagnostic studies.
- [Clinical peculiarities of diagnostics of sensorineural loss of hearing and deafness in the children.] [JOURNAL ARTICLE]
- Vestn Otorinolaringol 2014; (2):66-72.
The clinical features of various subjective and objective methods for the study of the hearing function were evaluated based on the results of examination of 46 children presenting with sensorineural hearing loss and deafness. The factors that influence the effectiveness and quality of diagnostics of sensorineural loss of hearing in the children were elucidated.
- [The analysis of disability caused by ear pathology in the adult population of Moscow during the period from 2007 to 2010.] [JOURNAL ARTICLE]
- Vestn Otorinolaringol 2014; (2):63-65.
Disability due to the loss of hearing is one of the main challenges to public health services and social protection of the population. The results of analysis performed by the author indicate the necessity of the comprehensive approach to the solution of disability problems for all social groups of the population. Special attention should be paid to the subpopulation of the able-bodied subjects with hearing disorders who need special medical and social rehabilitative measures to be developed and applied.
- [The new method for the analysis and visualization of the fine temporal structure of the transient evoked otoacoustic emission signal.] [JOURNAL ARTICLE]
- Vestn Otorinolaringol 2014; (2):58-62.
We have developed the new method for the analysis and visualization of the fine temporal structure of the transient evoked otoacoustic emission signal. The method consists of the presentation of the signal in the form of a set of tone components with a rapidly changing amplitude and relatively stable frequency. It is based on the combination of three spectrograms differing in frequency and temporal resolution by means of fuzzy logic amplitude estimation with subsequent frequency refining with the use of the least square procedure, reduction of the number of the insignificant components, and final re-ordering of the results for the simplification of further data processing. The new method was named Pitch Envelope Analysis (PEA). For data representation, a new type of diagram named componentogram was designed. The proposed method can be used for the real time processing of the continuous data stream especially for speech processing.