To evaluate the efficiency of treatment using various systemic radiotherapies for metastatic skeletal involvement in patients with breast or prostate cancer.The case histories of 350 patients treated at the Department of Radiation Medicine in 2006 to 2010 for multiple metastatic skeletal involvement in cancers at various sites were analyzed. The efficiency of treatment for pain syndrome and the magnitude of a myelosuppressive effect were estimated in the use of various systemic radiotherapies. For this, the authors compared: 1) two patient groups treated by 89Sr chloride monotherapy in the standard activity of 150 MBq or by that in combination with teleradiotherapy (TRT); 2) two patient groups treated by the monotherapy in the standard activity of 150 MBq or by 89Sr chloride fractional injection.The efficiency of treatment using various systemic radiotherapies was estimated. That was comparatively evaluated in the patient groups having various treatments. Algorithms of indications were elaborated to choose a systemic radiotherapy option depending on the clinical situation. An 89Sr chloride injection procedure was developed for patients with significant myelosuppression.1. Various systemic radiotherapies as second-line therapy may be used to treat metastatic skeletal involvement in patients with cancer at various sites. 2. The most pronounced analgesic effect was found when 89Sr chloride in the standard activity of 150 MBq had been injected in combination with TRT (a 36% reduction in the intensity of pain syndrome); a less pronounced effect was produced by 89Sr chloride monotherapy (27%). The lowest analgesic effect was observed when 89Sr chloride had been fractionally injected (14%). 3. The levels of white blood cells and platelets were decreased in all the groups. 4. 89Sr chloride fractional injection is the method of choice when its single administration is impossible in patients with evident leukocyto- and thrombocytopenia.

To improve the algorithm of pelvic X-ray study to enhance the efficiency of diagnosis of pelvic bone fractures.A total of 1.415 patients with pelvic injury were examined. Multi-projection X-ray study (an Apelem radiodiagnostic unit) and multislice spiral computed tomography (an Aquilion-32 multislice spiral scanner (Toshiba, Japan)) were performed.An algorithm for X-ray diagnosis of injuries of the pelvis and acetabulum has been elaborated, which will be able to significantly specify fracture detection.In the first diagnostic step in treating pelvic injuries, all patients must undergo multiprojection X-ray study in the anteroposterior and oblique projections, which will be able to reduce the percentage of diagnostic errors from 30 to 5%.

The results of ultrasound study of upper extremity tissues were comparatively analyzed in 74 patients with varying degrees of thermal burns. All the victims had thermal burns of the shoulder, forearm, and hand of one or both arms; the injured and contralateral normal areas were comparatively analyzed. The analysis of the findings has revealed that thermal burns of the upper extremities show certain ultrasound symptoms of soft tissue injuries that are indicative of the specific features of changes in the postburn period in relation to the degree of the injury - the duration of detection of edemas and fluid along the muscle bundles and tendon sheaths, their immobility during active and passive movements, the signs of extravasal compression, the determination of vascular wall complications, the signs of cartilaginous tissue damage, and articular complications.

The diagnosis of acute urinary tract infection and acute pyelonephritis in children is based on a set of clinical and laboratory manifestations. This paper analyzes the role of renal ultrasound study in patients with the first episode of pyelonephritis. A total of more than 1,000 children admitted to hospital with urinary tract infection were echographically examined. The most common echographic findings were pelvic wall thickening and renal enlargement. The paper also describes the rare variants of pyelonephritis: renal infiltrates and abscesses, pyelonephritis in the presence of obstructive uropathies, pyelonephritis as a cause of acute renal failure.

To estimate the left ventricular (LV) energy index from the data of 31P-magnetic resonance spectroscopy (31P-MRS) in patients with hypertrophic cardiomyopathy (HCM) versus healthy individuals.The investigation included 46 persons, including 30 healthy volunteers (Group 1) without cardiovascular diseases and 16 patients with HCM (Group 2). All the persons underwent cardiac magnetic resonance imaging (MRI) and 31P-MRS using a high-field Achieva 3T TX MRI scanner (Philips, Netherlands). ISIS location and adiabatic pulse with iterative shimming were used to collect data.The PC/ATP energy index (a phosphocreatine to adenosine triphosphate ratio) was employed to evaluate myocardial energy metabolism in the patients with HCM. The PC/ATP index was 2.08 +/- 0.35 in Group 1 and 1.32 +/- 3.3 in Group 2 (p < 0.05).31P-MRS may be used to determine the myocardial energy metabolism in patients with HCM.