We report a case of a 19 month old boy that presented with acneform eruption on his cheeks since birth. This condition was left untreated until the age of one. At that time the lesions developed into inflammatory nodules that resolved after topical treatment (Aknemycin fluid, cynober-sulfer pastae) and remission exist during 6 months. Based on presented case authors describe etiopatogenesis of acne and have done rewies of the literature regarding therapy, indications and safety of administration of oral retinoids to children.