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- Acute Oedema Blisters on a Skin Swelling: An Unusual Manifestation of Hereditary Angioedema. [JOURNAL ARTICLE]
- Acta Derm Venereol 2015 Oct 6.
- Laboratory tests for disorders of complement and complement regulatory proteins. [JOURNAL ARTICLE]
- Am J Hematol 2015 Oct 6.
- Snoring-Induced Vibratory Angioedema. [Journal Article]
- Am J Case Rep 2015.:700-2.
BACKGROUNDVibratory angioedema (VA) is a rare physical urticaria, with symptoms of itching and swelling of the skin or mucosa when it is exposed to vibration. Avoidance of vibration is the best way to manage this condition. This case report will assist physicians to diagnose this rare condition. Here, a previously unpublished potential successful treatment modality is being presented, with good symptom control, along with some photographs taken during an acute attack. A literature review points towards potential undiagnosed cases. CASE REPORT A 70-year-old woman had multiple emergency department visits for tongue and throat swelling over 3 years. The episodes always happened at night. Detailed history elicited some episodes of itching and swelling of hands when driving as well as significant snoring while sleeping. Physical examination was unremarkable except for morbid obesity. Complement factor 4 and C1esterase inhibitor level were within normal limits. A tentative diagnosis of angioedema induced by oropharyngeal vibration from snoring was made. A sleep study confirmed sleep apnea with severe snoring. After CPAP (continuous positive airway pressure) treatment, she had successful symptom control.
CONCLUSIONSSnoring-induced VA is very likely an under-diagnosed condition in the community. The typical history is the key to the diagnosis. This condition could be confirmed by vibration test or by the resolution of symptoms with elimination of vibration. Effective symptom control is possible by avoidance of oropharyngeal vibration from snoring with the administration of CPAP therapy, making it a potential novel indication for this condition.
- [Cutaneous loxoscelism mainly edematous: a case report]. [English Abstract, Journal Article]
- Rev Chilena Infectol 2015 Aug; 32(4):467-71.
- Food Allergy: Common Causes, Diagnosis, and Treatment. [Journal Article, Review]
- Mayo Clin Proc 2015 Oct; 90(10):1411-9.
- The safety of treatments for angioedema with hereditary C1 inhibitor deficiency. [JOURNAL ARTICLE]
- Expert Opin Drug Saf 2015 Oct 1.:1-12.
- Angiotensin-converting enzyme inhibitor-induced angioedema and icatibant: a new hope. [Letter]
- Intern Med J 2015 Oct; 45(10):1093-4.
- [Perioperative Management of a Patient with Hereditary Angioedema: A Case Report]. [English Abstract, Journal Article]
- Masui 2015 Apr; 64(4):441-3.
- Off-Label Use of Agents for Management of Serious or Life-threatening Angiotensin Converting Enzyme Inhibitor-Induced Angioedema. [REVIEW, JOURNAL ARTICLE]
- Ann Pharmacother 2015 Sep 28.
- Drug Hypersensitivity in children: report from the pediatric task force of the EAACI Drug Allergy Interest Group. [REVIEW, JOURNAL ARTICLE]
- Allergy 2015 Sep 28.