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2,527 results
  • Current management of low-grade gliomas. [Journal Article]
  • COCurr Opin Neurol 2016; 29(6):782-788
  • Hottinger AF, Hegi ME, Baumert BG
  • CONCLUSIONS: Regarding molecular prognostic factors, IDH wild-type LGGs have the worst prognosis, independent of therapy, whereas patients with mutated IDH, codeleted 1p/19q LGGs fared best regarding progression-free survival (PFS). In high-risk LGGs, PFS is similar regardless of whether patients have been treated with radiation or TMZ. In the second trial, patients who were treated with combination radiation and chemotherapy showed significant longer overall survival.
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