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- Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women. [JOURNAL ARTICLE]
- J Am Heart Assoc 2015; 4(10)
- Management of lipoprotein X and its complications in a patient with primary sclerosing cholangitis. [JOURNAL ARTICLE]
- Clin Lipidol 2015 Aug 1; 10(4):305-312.
- Gallstone and Severe Hypertriglyceride-Induced Pancreatitis in Pregnancy. [Journal Article]
- Obstet Gynecol Surv 2015 Sep; 70(9):577-83.
- Coenzyme Q10 and oxidative stress, the association with peripheral sensory neuropathy and cardiovascular disease in type 2 diabetes mellitus. [JOURNAL ARTICLE]
- J Diabetes Complications 2015 Aug 13.
- Obesity and Hyperlipidemia Modulate Alveolar Bone Loss in Wistar Rats. [JOURNAL ARTICLE]
- J Periodontol 2015 Sep 17.:1-15.
- Multiple Factors Related to the Secretion of Glucagon-Like Peptide-1. [Journal Article, Review]
- Int J Endocrinol 2015.:651757.
- Relationship Between Hyperuricemia and Cardiovascular Disease Risk Factors in a Chinese Population: A Cross-Sectional Study. [Journal Article]
- Med Sci Monit 2015.:2707-17.
BACKGROUNDTo study the relationship between hyperuricemia and cardiovascular diseases (CVDs) risk factors in a Chinese population. MATERIAL AND
METHODSData analyzed in this study were from the Chinese Hyperuricemia and Gout Database. Indicators of serum uric acid (SUA) level, height, weight, systolic blood pressure (SBP), diastolic blood pressure (DBP), smoking status, alcohol consumption, blood glucose, cholesterol, and triglycerides were measured. T test, one-way analysis of variance, Pearson's correlation, multivariate linear regression, and multivariate logistic regression were used.
RESULTSCompared with normouricemic men, hyperuricemic men had greater height (P<0.01), weight (P<0.001), body mass index (BMI) (P<0.001), SBP (P<0.01), DBP (P<0.001), cholesterol (P<0.01), and triglyceride (P<0.001). Compared with normouricemic women, hyperuricemic women were older (P<0.01) and had greater weight (P<0.05), BMI (P<0.01), SBP (P<0.01), DBP (P<0.05), glucose (P<0.05), and triglyceride (P<0.001). In men, an increase of 1 mg/dL in SUA was associated with a 0.279 kg/m2 increase in BMI (P<0.001), a 2.438 mg/dL increase in cholesterol (P<0.05), a 10.358 mg/dL increase in triglyceride (P<0.001), and a 3.1 mg/dL decrease in glucose (P<0.01). In women, an increase of 1 mg/dL SUA was associated with a 0.168 kg/m2 increase in BMI (P<0.01) and a 3.708 mg/dL increase in triglyceride (P<0.01). After adjustment, SUA was strongly associated with obesity and hyperlipidemia in both sexes.
CONCLUSIONSElevated serum uric acid concentration was strongly associated with obesity and hyperlipidemia in both men and women. These results indicated that, among hyperuricemia patients, we should pay more attention to the possibility of cardiovascular complications. These results might provide a novel target or a possible new treatment for cardiovascular diseases by lowering the level of serum uric acid.
- PCSK9 and triglyceride-rich lipoprotein metabolism. [REVIEW, JOURNAL ARTICLE]
- J Biomed Res 2015 Jul 20.
- Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters. [Journal Article, Research Support, Non-U.S. Gov't]
- J Transl Med 2015.:278.
- Lipoxin A4 and Neutrophil/Lymphocyte Ratio: A Possible Indicator in Achieved Systemic Risk Factors for Periodontitis. [Journal Article]
- Med Sci Monit 2015.:2485-93.