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- Demographic and Etiological Patterns of Gastric Outlet Obstruction in Kerala, South India. [JOURNAL ARTICLE]
- N Am J Med Sci 2015 Sep; 7(9):403-406.
- Rare medical manifestations of severe restricting and purging: "Zebras," missed diagnoses, and best practices. [JOURNAL ARTICLE]
- Int J Eat Disord 2015 Nov 23.
- Bioengineered human pyloric sphincters using autologous smooth muscle and neural progenitor cells. [JOURNAL ARTICLE]
- Tissue Eng Part A 2015 Nov 12.
- Polyradiculopathy and Gastroparesis due to Cytomegalovirus Infection in AIDS: A Case Report and Review of Literature. [Journal Article]
- Am J Case Rep 2015.:801-4.
BACKGROUNDCytomegalovirus (CMV) infection has been well described as an opportunistic infection of patients with human immunodeficiency virus (HIV). To the best of our knowledge, this is the first case report of a patient with AIDS and lumbosacral polyradiculopathy, associated with gastroparesis resulting from CMV infection. CASE REPORT A 46-year-old Hispanic woman with a history of HIV for 10 years was admitted to our hospital for nausea, vomiting, urinary retention, and generalized weakness. Bilateral lower extremity examination revealed flaccid paraplegia, decreased sensations from the groin downwards, bilateral lower extremity areflexia, and absent plantar reflexes, with enlarged urinary bladder. CMV was detected in CSF by PCR, and cervical and lumbar magnetic resonance imaging (MRI) revealed intense nodular leptomeningeal enhancement from the lower thoracic cord and extending along the conus medullaris/filum terminalis and nerve roots. Gastric emptying scintigraphy revealed severe delayed gastric emptying time. Ganciclovir was initiated and her neurological symptoms and gastrological symptoms gradually improved. Over 8 weeks, nausea and vomiting resolved and the patient was able to walk before being discharged from the hospital.
CONCLUSIONSPolyradiculopathy and gastroparesis can result from CMV infection in AIDS patients. Whether the mechanism is secondary to viral infection or immune systems remains unclear. It is important for physicians to be aware of this uncommon presentation in the antiretroviral therapy (ART) era. CMV treatment should be initiated immediately once diagnosis is confirmed.
- The relationship among gastroparetic symptoms, quality of life, and gastric emptying in patients referred for gastric emptying testing. [JOURNAL ARTICLE]
- Neurogastroenterol Motil 2015 Nov 7.
- Long-term outcomes of gastric electrical stimulation in children with gastroparesis. [JOURNAL ARTICLE]
- J Pediatr Surg 2015 Oct 23.
- [Functional and motor gastrointestinal disorders]. [English Abstract, Journal Article]
- Gastroenterol Hepatol 2015 Sep.:3-12.
- Psychological distress in Rome III functional dyspepsia patients presenting for testing of gastric emptying. [JOURNAL ARTICLE]
- Neurogastroenterol Motil 2015 Oct 28.
- Blunting of Colon Contractions in Diabetics with Gastroparesis Quantified by Wireless Motility Capsule Methods. [Journal Article]
- PLoS One 2015; 10(10):e0141183.
- Current and Emerging Medical Therapies for Gastroparesis. [Journal Article]
- Curr Treat Options Gastroenterol 2015 Dec; 13(4):452-72.