(Neurology AND Movement disorders) articles in PubMed
- Reliability and validity of a new dexterity questionnaire (DextQ-24) in Parkinson's disease. [Journal Article]
- Parkinsonism Relat Disord 2016 Sep 15PR
- CONCLUSIONS: The Dexterity Questionnaire 24 is valid and reliable for evaluating dexterity in patients with Parkinson's disease.
- The Practicalities of Assessing Freezing of Gait. [Journal Article]
- J Parkinsons Dis 2016 Sep 20JP
- CONCLUSIONS: To date, a unique methodological tool that encompasses the entire complexity of FOG is lacking. Combining methods should give a better picture of FOG severity, in accordance with the precise clinical or research context. Further development of any future assessment tool requires understanding and thorough analysis of the specific clinical expressions of FOG.
- Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases. [Journal Article]
- JAMA Neurol 2016 Sep 19JN
- CONCLUSIONS: Patients with Lewy body disease manifest a spectrum of tau pathology. Cortical aggregates of tau are common in patients with DLB and in PD-impaired patients, even in those without elevated amyloid levels. When present, tau deposition is associated with cognitive impairment. These findings support a role for tau copathology in the Lewy body diseases.
- Are Upper-Body Axial Symptoms a Feature of Early Parkinson's Disease? [Journal Article]
- PLoS One 2016; 11(9):e0162904Plos
- CONCLUSIONS: Upper body axial symptoms were frequent in men with early-stage PD, whereas women presented worst non-motor impairments. New assessment methods are required because currently available tools do not reliably detect these upper-body axial disorders.
- Bradykinesia in early and advanced Parkinson's disease. [Journal Article]
- J Neurol Sci 2016 Oct 15; 369:286-91JN
- CONCLUSIONS: The study yields an objective characterization of motor impairment in early and advanced PD. The kinematic assessment of the effects of selegiline on movement abnormalities in early PD provides a better understanding and interpretation of their pathophysiological mechanisms.
- Increased likelihood of anxiety and poor sleep quality in Parkinson's disease patients with pain. [Journal Article]
- J Neurol Sci 2016 Oct 15; 369:212-5JN
- CONCLUSIONS: Pain in PD seems to be linked with specific pain characteristics (akathisic, tension and sharp pain) as well as heightened anxiety and worsened sleep quality. Integrative approach treatments which address pain in PD may also improve anxiety and sleep quality.
- Focal status epilepticus and progressive dyskinesia: A novel phenotype for glycine receptor antibody-mediated neurological disease in children. [Journal Article]
- Eur J Paediatr Neurol 2016 Sep 12EJ
- CONCLUSIONS: Glycine receptor antibodies are associated with focal status epilepticus and seizures, encephalopathy and progressive dyskinesia and should be evaluated in autoimmune encephalitis.
- Dystonia in ATP2B3-associated X-linked spinocerebellar ataxia. [Letter]
- Mov Disord 2016 Sep 22MD
- Dyspraxia in ASD: Impaired coordination of movement elements. [Journal Article]
- Autism Res 2016 Sep 21AR
- Children with autism spectrum disorders (ASD) have long been known to have deficits in the performance of praxis gestures; these motor deficits also correlate with social and communicative deficits. ...
Children with autism spectrum disorders (ASD) have long been known to have deficits in the performance of praxis gestures; these motor deficits also correlate with social and communicative deficits. To date, the precise nature of the errors involved in praxis has not been clearly mapped out. Based on observations of individuals with ASD performing gestures, we hypothesized that the simultaneous execution of multiple movement elements is especially impaired in affected children. We examined 25 school-aged participants with ASD and 25 age-matched controls performing seven simultaneous gestures that required the concurrent performance of movement elements and nine serial gestures, in which all elements were performed serially. There was indeed a group × gesture-type interaction (P < 0.001). Whereas both groups had greater difficulty performing simultaneous than serial gestures, children with ASD had a 2.6-times greater performance decrement with simultaneous (vs. serial) gestures than controls. These results point to a potential deficit in the simultaneous processing of multiple inputs and outputs in ASD. Such deficits could relate to models of social interaction that highlight the parallel-processing nature of social communication. Autism Res 2016,. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.
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- Nigral and striatal connectivity alterations in asymptomatic LRRK2 mutation carriers: A magnetic resonance imaging study. [Journal Article]
- Mov Disord 2016 Sep 21MD
- CONCLUSIONS: Asymptomatic LRRK2 mutation carriers showed functional connectivity changes in striatocortical and nigrocortical circuits compared with noncarriers. These findings support the concept that altered brain connectivity precedes the onset of classical motor features in a genetic form of PD. © 2016 International Parkinson and Movement Disorder Society.