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Pulmonary infarction, pleural effusion in [keywords]
- Dilated cardiomyopathy in a De Brazza's monkey (Cercopithecus neglectus). [Journal Article]
- J Med Primatol 2014 Jun; 43(3):209-12.
Cardiomyopathies have been reported in many primates. They may result from an inflammatory response to an infectious agent, nutritional deficiency, familial-genetic inheritance or toxic agents, but in many cases they are idiopathic.A De Brazza's monkey (Cercopithecus neglectus) presented with weight loss and inappetence. Physical examination, blood collection and diagnostic imaging and an electrocardiogram were performed.Radiographs and echocardiogram revealed pleural effusion with partially collapsed lungs, cardiomegaly, and reduced myocardial contractility from myocardial failure.Necropsy revealed pulmonary infarction, subsequent to heart failure from dilated cardiomyopathy.
- Middle cerebral artery infarction in a cancer patient: a fatal case of Trousseau's syndrome. [Journal Article]
- Hong Kong Med J 2014 Feb; 20(1):74-7.
Trousseau's syndrome is defined as any unexplained thrombotic event that precedes the diagnosis of an occult visceral malignancy or appears concomitantly with a tumour. This report describes a young, previously healthy man diagnosed to have an acute middle cerebral arterial ischaemic stroke and lower-limb deep vein thrombosis, who subsequently succumbed to pulmonary arterial embolism. During the course of his illness, he was diagnosed to have a malignant pleural effusion secondary to an occult adenocarcinoma. This report highlights the need for a high degree of suspicion for occult malignancy and non-bacterial thrombotic endocarditis in young (<60 years old) ischaemic stroke patients with no identifiable conventional cardiovascular risks. In selected patients, transoesophageal echocardiography is the diagnostic investigation of choice, since transthoracic imaging is not sensitive. Screening tests for serum tumour markers and prompt heparinisation of these patients are suggested whenever ischaemic stroke secondary to malignancy-induced systemic hypercoagulability is suspected.