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- Optimization of multi-pulse sequences for nonlinear contrast agent imaging using a cMUT array. [JOURNAL ARTICLE]
- Phys Med Biol 2015 Mar 24; 60(8):3111-3127.
- Posterior reversible encephalopathy syndrome as presenting form of very early systemic sclerosis. [Journal Article]
- Case Rep Neurol Med 2015.:290378.
Introduction.Posterior Reversible Encephalopathy Syndrome (PRES) is an increasingly recognized clinical and radiological entity with a wide spectrum of symptoms. Its mechanism depends on failure of the blood-brain barrier due to high systemic blood pressure (BP) and loss of integrity of vascular endothelium related with different triggers. Methods. We aim to report a case of PRES induced by arterial hypertension and very early systemic sclerosis (SSc) not previously known.
Results.A 64-year-old female was admitted due to 1-week pulsating headache more prominent on frontal scalp, accompanied by phonophobia, photophobia, and facial flushing. Neurological exam revealed brisk deep tendon reflex. Brain magnetic resonance imaging (MRI) showed subcortical lesions mainly located in posterior regions. BP was monitored and episodic arterial hypertension was detected. In laboratory tests positive anti-topoisomerase I antibodies were detected. BP was controlled with angiotensin-converting-enzyme inhibitors and headache improved. In a new MRI a month later improvement of white matter lesions was observed. Capillaroscopy showed "active pattern," considered typical of SSc.
Conclusion.In SSc anti-endothelial cell antibodies impair vascular endothelium and liberation of vasoconstrictors leads to BP increasing and disruption of blood-brain barrier autoregulation mechanisms. PRES can be the first manifestation of very early SSc and this entity should be considered even in absence of skin lesions or Raynaud phenomenon.
- The GoMo Study: Randomized clinical trial assessing neonatal pain with Gomco versus Mogen Clamp Circumcision. [JOURNAL ARTICLE]
- Am J Obstet Gynecol 2015 Mar 17.
- No association of maternal gestational weight gain with offspring blood pressure and hypertension at age 18 years in male sibling-pairs: a prospective register-based cohort study. [Journal Article]
- PLoS One 2015; 10(3):e0121202.
- [278-POS]: A genetic connection between preeclampsia and chronic hypertension in Norwegian families. [Journal Article]
- Pregnancy Hypertens 2015 Jan; 5(1):138-9.
- Does reduced myocardial efficiency in systemic hypertensive-hypertrophy correlate with increased left-ventricular wall thickness? [JOURNAL ARTICLE]
- Hypertens Res 2015 Mar 19.
- A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension. [Journal Article]
- PLoS Genet 2015 Mar; 11(3):e1005035.
- The study of cardiovascular risk in adolescents - ERICA: rationale, design and sample characteristics of a national survey examining cardiovascular risk factor profile in Brazilian adolescents. [Journal Article]
- BMC Public Health 2015 Dec.:1442.
- Wide awake technique versus local anesthesia with tourniquet application for minor orthopedic hand surgery: a prospective clinical trial. [Journal Article]
- J Med Assoc Thai 2015 Jan; 98(1):106-10.
- Initial tourniquet pressure does not affect tourniquet arterial occlusion pressure. [Journal Article]
- J Spec Oper Med 2015; 15(1):39-49.