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- Neurocognitive, psychiatric, and substance use characteristics in opioid dependent adults. [JOURNAL ARTICLE]
- Addict Behav 2016 Mar 31.:137-143.
- Buprenorphine Prescribing: To Expand or Not to Expand. [Journal Article]
- J Psychiatr Pract 2016 May; 22(3):183-92.
- Design of a randomized controlled trial of extended-release naltrexone versus daily buprenorphine-naloxone for opioid dependence in Norway (NTX-SBX). [Journal Article]
- BMC Pharmacol Toxicol 2016; 17(1):18.
- Implementing opioid substitution in Lebanon: Inception and challenges. [JOURNAL ARTICLE]
- Int J Drug Policy 2016 Feb 23.
- Perceptions Related to Pharmacological Treatment of Opioid Dependence Among Individuals Seeking Treatment at a Tertiary Care Center in Northern India: A Descriptive Study. [JOURNAL ARTICLE]
- Subst Use Misuse 2016 Apr 21.:1-9.
- Criminal Charges Prior to and After Enrollment in Opioid Agonist Treatment: A Comparison of Methadone Maintenance and Office-based Buprenorphine. [JOURNAL ARTICLE]
- Subst Use Misuse 2016 Apr 20.:1-9.
- Use of Psychotropic Drug Urine Test Strips in Opiate Maintenance Therapy: A Clinical Assessment of Its Advantages. [JOURNAL ARTICLE]
- Subst Abus 2016 Apr 19.:0.
- Simultaneous quantification of buprenorphine, naloxone and phase I and II metabolites in plasma and breastmilk by liquid chromatography-tandem mass spectrometry. [Journal Article]
- J Chromatogr A 2016 May 13.:70-7.
- Impact of Opioid and Nonopioid Drugs on Postsurgical Pain Management in the Rat. [Journal Article]
- Pain Res Treat 2016.:8364762.
Aim.Nonsteroidal anti-inflammatory drugs or opioids are commonly used to control surgical pain following veterinary and clinical procedures. This study evaluated the efficacy of postoperative ketorolac or buprenorphine following abdominal surgery. Main Methods. Mean arterial pressure (MAP), heart rate, animal activity, corticosterone levels, and a nociceptive sensitivity assay were used to evaluate 18 adult male Sprague-Dawley rats which underwent aortic artery occlusion for implantation of a radiotelemetry device. The animals were treated postoperatively with intraperitoneal injections of vehicle, ketorolac (10 mg/kg), or buprenorphine (0.06 mg/kg) every 8 hours for 3 days. Key Findings. There were no consistent significant changes in any of the telemetry parameters after treatment with ketorolac compared with no saline treatment with the exception of increased MAP in the buprenorphine group during the first 48 hours when compared with other treatment groups. There was a sustained increase in fecal corticosterone levels from baseline on days 2-7 with buprenorphine compared with vehicle- or ketorolac-treated animals. All treatment conditions displayed reduced paw withdrawal thresholds (PWTs) from day 1 to day 21 following surgery. Compared with the vehicle treatment group, buprenorphine-treated animals exhibited significantly lower PWT levels from day 4 to 14 days. Significance. Given the prolonged increase in fecal corticosterone levels and pronounced changes in tactile hyperalgesia behavior in rodents subjected to buprenorphine treatment, these data suggest that ketorolac may be superior to buprenorphine for the treatment of postprocedure pain behavior in rodents.
- Factors associated with non-adherence and misuse of opioid maintenance treatment medications and intoxicating drugs among Finnish maintenance treatment patients. [Journal Article]
- Drug Alcohol Depend 2016 May 1.:227-35.