Download the Free Prime PubMed App to your smartphone or tablet.

Available for iPhone or iPad:

Unbound PubMed app for iOS iPhone iPadAlso Available:
Unbound PubMed app for Android

Available for Mac and Windows Desktops and laptops:

Unbound PubMed app for WindowsUnbound PubMed app for MAC OS Yosemite Macbook Air pro
(diethylstilbestrol diethylstilbestrol)
10,486 results
  • Synthesis and basic evaluation of 7α-(3-[(18)F]fluoropropyl)-testosterone and 7α-(3-[(18)F]fluoropropyl)-dihydrotestosterone. [Journal Article]
  • ANAnn Nucl Med 2016 Sep 28
  • Okamoto M, Naka K, … Toyohara J
  • CONCLUSIONS: [(18)F]15 is better than [(18)F]7 in terms of radiochemical yield, in vitro binding affinity, prostate specific binding and stability against in vivo metabolic de-fluorination. However, the net uptake level of [(18)F]15 in prostate might be insufficient for in vivo visualization. Although [(18)F]7 and [(18)F]15 improved in vivo stability against de-fluorination, other basic characterization data in rodents were not superior to the current standard tracer 16β-[(18)F]fluoro-5α-dihydrotestosterone. It is also revealed that the shorter side chain length of 7α-[(18)F]fluoromethyl-dihydrotestosterone is superior to the longer three carbon chain in [(18)F]15, in terms of net prostate uptake and in vivo metabolic stability.
New Search Next