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21,875 results
  • Hysterectomies in Portugal (2000-2014): What has changed? [Journal Article]
  • EJEur J Obstet Gynecol Reprod Biol 2016 Nov 21; 208:97-102
  • Gante I, Medeiros-Borges C, Águas F
  • CONCLUSIONS: In Portugal, the rate of hysterectomies decreased in the last 15 years with an increase in age at the time of the procedure and a change towards less invasive routes. Uterine fibroids remain the major indication for hysterectomy. Additionally, we noted a significant shift towards more concomitant bilateral salpingectomy (and less bilateral adnexectomy) during hysterectomy for benign indications, according to the evidence suggesting the fallopian tube as the origin of ovarian cancer.
  • Primary iris leiomyoma. [Journal Article]
  • SOSurv Ophthalmol 2016 Nov 24
  • Yeaney GA, Platt S, Singh AD
  • Intraocular leiomyomas are uncommon and usually occur in the ciliary body. Primary leiomyoma of the iris is both rare and a difficult diagnosis to make, given melanocytic tumors are more common and m...
  • Highly heterogeneous genomic landscape of uterine leiomyomas by whole exome sequencing and genome-wide arrays. [Journal Article]
  • FSFertil Steril 2016 Nov 23
  • Yatsenko SA, Mittal P, … Rajkovic A
  • CONCLUSIONS: Mutations in genes implicated in cell-to-cell interactions and remodeling of the extracellular matrix and genomic aberrations involving genes coding for the Mediator complex subunits were identified in uterine leiomyomas. Additionally, we discovered that ∼4.6% of leiomyosarcomas harbored MED12 exon 2 mutations, but the relevance of this association with molecular pathogenesis of leiomyosarcoma remains unknown.
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