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ideal body weight [keywords]
- Sugammadex and ideal body weight in bariatric surgery: the debate continues. [Journal Article]
- Anesthesiol Res Pract 2014.:762432.
- Modifying Health Behavior to Prevent Cardiovascular Diseases: A Nationwide Survey among German Primary Care Physicians. [Journal Article]
- Int J Environ Res Public Health 2014; 11(4):4218-32.
Cardiovascular diseases (CVD) are a major public health concern as they are the leading cause of death in developed countries. Primary care is considered to be the ideal setting for CVD prevention. Therefore, more than 4,000 German primary care physicians (PCPs) were asked about their attitudes towards and their activities regarding the prevention of CVD in the nationwide ÄSP-kardio Study. The focus of the study was on health behavior modification. Two thirds of the participating PCPs stated that they routinely provided brief inventions to assist patients in reducing both their tobacco (72%) and alcohol (61%) consumption, to encourage them to increase their levels of physical activity (72%), and to assist them in adjusting to a more healthy diet (66%), and in achieving a healthy body weight (69%). However, only between 23% (quitting smoking) and 49% (diet modification) of PCPs felt that they had been successful in helping patients modify their lifestyles. Insufficient reimbursement, cultural diversity and a lack of time were reported to be the most problematic barriers to successful intervention in the primary care setting. Despite these obstacles, the majority of German PCPs was engaged in prevention and health behavior intervention to reduce the incidence and progression of CVD.
- Association between excess body weight and urine protein concentration in healthy dogs. [JOURNAL ARTICLE]
- Vet Clin Pathol 2014 Apr 14.
Markedly overweight people can develop progressive proteinuria and kidney failure secondary to obesity-related glomerulopathy (ORG). Glomerular lesions in dogs with experimentally induced obesity are similar to those in people with ORG.The aim of this study was to evaluate if urine protein and albumin excretion is greater in overweight and obese dogs than in dogs of ideal body condition.Client-owned dogs were screened for underlying health conditions. These dogs were assigned a body condition score (BCS) using a 9-point scoring system. Dogs with a BCS of ≥ 6 were classified as being overweight/obese, and dogs with a BCS of 4 or 5 were classified as being of ideal body weight. The urine protein:creatinine ratio (UPC) and urine albumin:creatinine ratio (UAC) were then determined, and compared between 20 overweight/obese dogs and 22 ideal body weight control dogs.Median UPC (0.04 [range, 0.01-0.14; interquartile range, 0.07]) and UAC (0.41 [0-10.39; 3.21]) of overweight/obese dogs were not significantly different from median UPC (0.04 [0.01-0.32; 0.07]) and UAC (0.18 [0-7.04; 1.75]) in ideal body weight dogs.Clinicopathologic abnormalities consistent with ORG were absent from overweight/obese dogs in this study.
- Extravascular Lung Water, B-Type Natriuretic Peptide, and Blood Volume Contraction Enable Diagnosis of Weaning-Induced Pulmonary Edema. [JOURNAL ARTICLE]
- Crit Care Med 2014 Apr 8.
We tested whether the changes in extravascular lung water indexed for ideal body weight could detect weaning-induced pulmonary edema. We also studied the diagnostic value of blood volume contraction indices and B-type natriuretic peptide variations.Prospective study.Twenty-one patients who failed a first spontaneous breathing trial.None.We performed a second 60-minute T-tube spontaneous breathing trial. Before and at the end of spontaneous breathing trial, we recorded pulmonary artery occlusion pressure, the extravascular lung water indexed for ideal body weight, plasma B-type natriuretic peptide level, hemoglobin, and plasma protein concentrations. Weaning-induced pulmonary edema was defined by the association of signs of clinical intolerance and a pulmonary artery occlusion pressure greater than or equal to 18 mm Hg at the end of spontaneous breathing trial. Because some patients performed several spontaneous breathing trial, a primary analysis included all spontaneous breathing trial and a secondary analysis included only the first spontaneous breathing trial of each patient. In primary analysis, 36 spontaneous breathing trials were analyzed, 21 spontaneous breathing trial with weaning-induced pulmonary edema and 15 without. During spontaneous breathing trial, extravascular lung water indexed for ideal body weight increased only in cases with weaning-induced pulmonary edema (25% ± 23%). Plasma protein concentration, hemoglobin concentration, and B-type natriuretic peptide also significantly increased only in cases with weaning-induced pulmonary edema (9% ± 3%, 9% ± 4%, 21% ± 23%, respectively). The areas under the receiver operating characteristics curves to detect weaning-induced pulmonary edema were 0.89 (95% CI, 0.78-0.99) for extravascular lung water indexed for ideal body weight, 0.97 (0.93-1.01) for spontaneous breathing trial-induced changes in plasma protein concentration, 0.96 (0.90-1.01) for changes in hemoglobin concentration, and 0.76 (0.60-0.93) for changes in B-type natriuretic peptide. An increase in extravascular lung water indexed for ideal body weight greater than or equal to 14% diagnosed weaning-induced pulmonary edema with a sensitivity of 67% (95% CI, 43-85%) and a specificity of 100% (95% CI, 78-100%). The secondary analysis confirmed these results.Spontaneous breathing trial-induced increases in extravascular lung water indexed for ideal body weight, plasma protein concentrations, hemoglobin concentration, and B-type natriuretic peptide are reliable alternatives to the pulmonary artery catheter for diagnosing weaning-induced pulmonary edema.
- Comparison of the plantar pressure distributions at different degrees of tilting: a preliminary report. [Journal Article]
- J Phys Ther Sci 2014 Mar; 26(3):401-3.
[Purpose] The purpose of this study was to investigate the amount of plantar pressures on the lower limb during tilt table standing and to indicate the ideal degree of tilting for partial weight bearing. [Subjects and Methods] Fifteen healthy subjects between the ages of 20 and 30 were recruited as volunteers for this study. All the measurements were taken while standing on a tilt table according to different inclination angles. [Results] The plantar pressures for 60° tilt table standing were lower by 7-9% of total body weight than the pressures during tilt table standing at 90°, and the pressures for 30° tilt table standing were lower by 18-20% of total body weight than the pressures for tilt table standing at 90°. [Conclusion] Standing training on a 60° tilt table might be equivalent to 80% of full weight bearing training, and tilt table standing training at 30° might be equivalent to 60% of full weight bearing training.
- Associations of serum uric acid levels with cardiovascular health factors: Differences by sex, age and body mass index in Chinese participants. [JOURNAL ARTICLE]
- Eur J Intern Med 2014 Apr 1.
Recently, the American Heart Association developed a set of 3 ideal cardiovascular (CV) health factors. However, information on whether associations of uric acid (UA) with the CV health factors is influenced by sex, age, and body mass index (BMI) is limited.We conducted a cross-sectional analysis using a cohort of 10,420 people aged 20-100years, who underwent health checkups in 2009. CV health factors were defined as untreated total cholesterol (TC)<200mg/dl, untreated systolic/diastolic blood pressure (BP)<120/80mmHg, and untreated fasting plasma glucose (FPG)<100mg/dl.The association of UA with each CV health factor was gender-specific. The interaction terms (gender×UA level) comparing change in prevalence of each CV health factor between the 1st and 4th UA quartiles showed a significantly greater reduction among women (all P<0.01). In addition, the interactions between UA levels and age on prevalence of each CV health factor were statistically significant (all P<0.01). Furthermore, absolute reductions in the prevalence of ideal levels of BP, and TC across ordinal UA quartiles were greater in obese individuals than in overweight and normal-weight individuals (all P<0.01). Finally, UA showed a bell-curved relation with the prevalence of ideal FPG among all BMI categories.Elevated UA inversely associated with each CV health factor and these associations were influenced by gender, age and BMI. Elevated UA levels should alert clinical suspicion for a potential coexistence of low frequency of CV health factors.
- Open lung approach with low tidal volume mechanical ventilation attenuates lung injury in rats with massive brain damage. [JOURNAL ARTICLE]
- Crit Care 2014 Apr 2; 18(2):R59.
The ideal ventilation strategy for patients with massive brain damage requires better elucidation. We hypothesized that in the presence of massive brain injury, a ventilation strategy using low (6 milliliters per kilogram ideal body weight) tidal volume (VT) ventilation with open lung positive end-expiratory pressure (LVT/OLPEEP) set according to the minimal static elastance of the respiratory system, attenuates the impact of massive brain damage on gas-exchange, respiratory mechanics, lung histology and whole genome alterations compared with high (12 milliliters per kilogram ideal body weight) VT and low positive end-expiratory pressure ventilation (HVT/LPEEP).In total, 28 adult male Wistar rats were randomly assigned to one of four groups: 1) no brain damage (NBD) with LVT/OLPEEP; 2) NBD with HVT/LPEEP; 3) brain damage (BD) with LVT/OLPEEP; and 4) BD with HVT/LPEEP. All animals were mechanically ventilated for six hours. Brain damage was induced by an inflated balloon catheter into the epidural space. Hemodynamics was recorded and blood gas analysis was performed hourly. At the end of the experiment, respiratory system mechanics and lung histology were analyzed. Genome wide gene expression profiling and subsequent confirmatory quantitative polymerase chain reaction (qPCR) for selected genes were performed.In NBD, both LVT/OLPEEP and HVT/LPEEP did not affect arterial blood gases, as well as whole genome expression changes and real-time qPCR. In BD, LVT/OLPEEP, compared to HVT/LPEEP, improved oxygenation, reduced lung damage according to histology, genome analysis and real-time qPCR with decreased interleukin 6 (IL-6), cytokine-induced neutrophil chemoattractant 1 (CINC)-1 and angiopoietin-4 expressions. LVT/OLPEEP compared to HVT/LPEEP improved overall survival.In BD, LVT/OLPEEP minimizes lung morpho-functional changes and inflammation compared to HVT/LPEEP.
- Effects of Viewing a Pro-Ana Website: An Experimental Study on Body Satisfaction, Affect, and Appearance Self-Efficacy. [JOURNAL ARTICLE]
- Eat Disord 2014 Apr 1.
Pro-anorexia websites portray an extreme form of thin-ideal. This between-subjects experiment examined the effects of viewing such a website on body satisfaction, affect, and appearance self-efficacy compared to viewing control websites (fashion, home decoration, automutilation). The sample consisted of 124 normal weight, young adult, Dutch women (mean age 21.2, mean body mass index 21.4). Participants did not differ on affect and appearance self-efficacy. One body satisfaction measure showed that pro-anorexia viewers were more satisfied with their bodies than home decoration viewers. Our findings suggest that viewing a pro-anorexia website might not have detrimental effects on body satisfaction and affect among normal weight young women.
- Drug dosage in isolated limb perfusion: evaluation of a limb volume model for extremity volume calculation. [Journal Article]
- World J Surg Oncol 2014; 12(1):81.
Exact drug dosing in isolated limb perfusion (ILP) and infusion (ILI) is essential. We developed and evaluated a model for calculating the volume of extremities and compared this model with body weight- and height-dependent parameters.The extremity was modeled by a row of coupled truncated cones. The sizes of the truncated cone bases were derived from the circumference measurements of the extremity at predefined levels (5 cm). The resulting volumes were added. This extremity volume model was correlated to the computed tomography (CT) volume data of the extremity (total limb volume). The extremity volume was also correlated with the patient's body weight, body mass index (BMI) and ideal body weight (IBW). The no-fat CT limb volume was correlated with the circumference-measured limb volume corrected by the ideal-body-weight to actual-body-weight ratio (IBW corrected-limb-volume).The correlation between the CT volume and the volume measured by the circumference was high and significant. There was no correlation between the limb volume and the bare body weight, BMI or IBW. The correlation between the no-fat CT volume and IBW-corrected limb volume was high and significant.An appropriate drug dosing in ILP can be achieved by combining the limb volume with the simple circumference measurements and the IBW to body-weight ratio.
- A74: nutritional and metabolic assessment in girls with systemic lupus erythematosus. [Journal Article]
- Arthritis Rheumatol 2014 Mar.:S106.
Cardiovascular disease (CVD), specifically from atherosclerosis, is one of major cause of morbidity and mortality in SLE. Given their lifelong exposure to atherogenic risk factors, children and adolescents with SLE are at particularly high risk of developing premature atherosclerosis and are therefore ideal candidates for primary prevention. Nutritional and metabolic status and inflammatory biomarkers have been consistently associated with the presence of CVD in multiple studies from different populations. The aim of our study was to evaluate nutritional status, homocysteine, vitamin B12, folate, lipoproteins, TNF-alfa, highsensitivity C-reactive protein (hs-CRP) concentrations and food intake in pediatric SLE patients and in healthy controls.Nineteen girls with SLE (group 1) and thirty-nine healthy girls (group 2) with the same age range were included in the study. SLE activity was assessed using SLEDAI. Clinical and nutritional evaluation including weight, height, waist circumference and body mass index (BMI) was performed. Plasma homocysteine, vitamin B12, folate, TNF-alfa, and hs-CRP concentrations were analyzed by chemiluminescent technique, lipoproteins were measured using colorimetric method and cholesterol by enzymatic standard method. Food intake was assessed using a 24 hour-recall questionnaire validated for our population and analyzed using the software DietWin version 1997-2002.The average age of SLE patients and controls was 15.5 and 14.6, varying from 12 to 18 and 10 to 18 y, respectively. There were no significant differences regarding age (p = 0,117), pubertal stage (breast p = 0,158 and pubis p = 0,578) and nutritional status (p = 0,107) between groups. The majority of SLE patients (16/19) had active disease and have been receiving prednisone for a mean period of 5 years. Body mass index, waist circumference and systolic blood pressure (SBP) values were statistically higher in SLE group when compared to healthy girls: 24.6 × 20.9 kg/m(2) , p = 0.003; 79.7 × 72.6 cm, p = 0.004 and 107.5 × 101.7 mmHG, p = 0.044, respectively, but height was statistically lower (1.55 × 1.61 m, p = 0.012). Homocysteine, vitamin B12, TNF-α and hs-CRP levels were higher in SLE subjects when compared to healthy controls: 8.6 × 7.3 mmol/L, p = 0.023; 616.9 × 444.0 pmol/L, p = 0.008; 8.7 × 7.1 pg/ml, p = 0.022; 4.4 × 0.8 mg/L, p = 0.002, respectively. Plasma folate and HDL-cholesterol were lower in SLE patients compared to controls: 12.2 × 14.0 ng/ml, p = .022 and 37.6 × 44.1 mg/dL, p = 0.008, respectively). There were no significant differences in energy, macronutrients, vitamin B12, folate and pyridoxine intake between groups.Increased risk factors to cardiovascular disease such as high BMI, WC, SBP, homocysteine, TNF-alpha and C-reactive protein, in addition to low folate and HDL levels, were found in this group of SLE patients when compared to healthy controls, and food intake was comparable in both groups. Our results may signalize future cardiovascular complications in SLE pediatric patients and possible associations between nutritional status and risk factors. This study is sponsored by FAPESP (number 2011/16141-7).