- Marital history and survival after a heart attack. [Journal Article]
- SSSoc Sci Med 2016 Oct 15; 170:114-123
- Heart disease is the leading cause of death in the United States and nearly one million Americans will have a heart attack this year. Although the risks associated with a heart attack are well establ...
Heart disease is the leading cause of death in the United States and nearly one million Americans will have a heart attack this year. Although the risks associated with a heart attack are well established, we know surprisingly little about how marital factors contribute to survival in adults afflicted with heart disease. This study uses a life course perspective and longitudinal data from the Health and Retirement Study to examine how various dimensions of marital life influence survival in U.S. older adults who suffered a heart attack (n = 2197). We found that adults who were never married (odds ratio [OR] = 1.73), currently divorced (OR = 1.70), or widowed (OR = 1.34) were at significantly greater risk of dying after a heart attack than adults who were continuously married; and the risks were not uniform over time. We also found that the risk of dying increased by 12% for every additional marital loss and decreased by 7% for every one-tenth increase in the proportion of years married. After accounting for more than a dozen socioeconomic, psychosocial, behavioral, and physiological factors, we found that current marital status remained the most robust indicator of survival following a heart attack. The implications of the findings are discussed in the context of life course inequalities in chronic disease and directions for future research.
- Effects of noise on telephone calls to the Madrid Regional Medical Emergency Service (SUMMA 112). [Journal Article]
- EREnviron Res 2016 Oct 19; 152:120-127
- CONCLUSIONS: SUMMA 112 data give access to real-time information on the health effects associated with increases in noise levels, which cannot be obtained via mortality or hospital-admission data, since these are collected in the longer term. Accordingly, this is something that would be immediately applicable in any future implementation of a syndromic surveillance system focusing on the effects of environmental pollutants on health.
- Risks, consequences, and prevention of falls of older people in oral healthcare centers. [Journal Article]
- SCSpec Care Dentist 2016 Oct 22
- One-third of community-dwelling people older than 65 years of age fall each year, and half of them fall at least twice a year. Older care home residents are approximately three times more likely to f...
One-third of community-dwelling people older than 65 years of age fall each year, and half of them fall at least twice a year. Older care home residents are approximately three times more likely to fall when compared to community-dwelling older people. Risk indicators for falls are related to the older people's body, environment, behavior, and activities. An important health risk indicator is (orthostatic or postprandial) hypotension, which may induce cerebral hypoperfusion. Although the majority of falls remain without major consequences, 10% to 25% of falls in care homes result in bodily trauma. Prevalent fall-related injuries are brain injury, lower extremity fracture including hip fracture and forearm/wrist fracture, facial fracture, humeral fracture, and rib/scapular fracture. As fall accidents by older people can have severe consequences, prevention of falls is of paramount importance. Healthcare providers, including oral healthcare providers, should inform older people on risks of falling and draw attention to potentially hazardous arrangements.
- ESUR recommendations for MR imaging of the sonographically indeterminate adnexal mass: an update. [Journal Article]
- EREur Radiol 2016 Oct 21
- CONCLUSIONS: • MRI is a useful complementary imaging technique for assessing sonographically indeterminate masses. • Categorization allows confident diagnosis in the majority of adnexal masses. • Type 3 contrast enhancement curve is a strong indicator of malignancy. • In sonographically indeterminate masses, complementary MRI assists in triaging patient management.
- Improved method for effective screening of ACC (1-aminocyclopropane-1-carboxylate) deaminase producing microorganisms. [Journal Article]
- JMJ Microbiol Methods 2016 Oct 18; 131:102-104
- Aminocyclopropane-1-carboxylate deaminase (ACCD) producing microorganisms support plant growth under a variety of biotic and abiotic stress conditions such as drought, soil salinity, flooding, heavy ...
Aminocyclopropane-1-carboxylate deaminase (ACCD) producing microorganisms support plant growth under a variety of biotic and abiotic stress conditions such as drought, soil salinity, flooding, heavy metal pollution and phyto-pathogen attack. Available screening methods for ACCD give idea only about its primary microbial ACCD activity than the actual potential. In the present investigation, we have simply improved screening method by incorporating pH indicator dyes (phenol red and bromothymol blue) in ACC containing medium. This modification is based on the basic principle that ACCD action releases ammonia which can be detected by color change and zone around the bacterial colony. High color intensity and zone around the colony indicates most potent producer, colony showing only a color change indicates moderate potential and no change in colony color indicates least efficiency. Enzymatic bioassays as well as root elongation studies revealed that ACC-deaminase activity of Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Bacillus subtilis clearly corresponds to their growth on dye incorporated ACC medium. This method could be used to complement the existing screening methods and to speed up the targeted isolation of agriculturally important microorganisms.
- Pre-existing risk factors for in-hospital death among older patients could be used to initiate end-of-life discussions rather than Rapid Response System calls: a case-control study. [Journal Article]
- RResuscitation 2016 Oct 18
- CONCLUSIONS: In a sample of older deteriorated patients requiring a RRS attendance, multiple indicators of chronic illness, cognitive impairment and frailty were significantly associated with high risk of death. These clinical features beyond the evident orders for limitation of medical treatment should signal the need for clinicians to initiate end-of-life discussions that may prevent futile interventions.
- The short term burden of ambient particulate matters on non-accidental mortality and years of life lost: A ten-year multi-district study in Tianjin, China. [Journal Article]
- EPEnviron Pollut 2016 Oct 18
- Years of life lost (YLL) is a more informative and accurate indicator than daily death counts for assessing air pollution related premature death. However, there is limited evidence available about t...
Years of life lost (YLL) is a more informative and accurate indicator than daily death counts for assessing air pollution related premature death. However, there is limited evidence available about the relationship of air pollution with YLL, especially in China. We conducted a ten-year (from January 1st, 2001 to December 31st, 2010) multi-district time-series study to estimate the effects of ambient particulate matter with an aerodynamic diameter of less than 10 μm in size (PM10) on daily non-accidental deaths and YLL in six districts of Tianjin, China. Meta-analysis was used to merge the results of the six districts. We found that the increase of PM10 was significantly associated with daily death and YLL in the six districts, except with the YLL in Heping district. 10 μg/m(3) increases in PM10 were associated with the maximum increases in excess risk (ER) of death counts of 0.33% (95% confidence interval [CI]: 0.25%, 0.41%) at lag01 and in YLL of 0.80 (95%CI: 0.47, 1.13) person year at lag01 for the combined effects of six districts, respectively. Moreover, the associations of PM10 on daily death counts and YLL were stronger in the elder people (≥65 years) than those in the younger ones (<65 years). These findings may help to shed light on the policy-making of PM-control in China and provide useful information for the protection of susceptible population.
- Lesser tuberosity cysts and their relationship with subscapularis tears and subcoracoid impingement. [Journal Article]
- JOJ Orthop Sci 2016 Oct 18
- CONCLUSIONS: The LTCs were significantly associated with subscapularis tears, and could be used as an indicator in the interpretation of MRI scans. However, there was no relationship between the subcoracoid impingement and LTCs.
- A cyanine-based near-infrared fluorescent probe for highly sensitive and selective detection of hypochlorous acid and bioimaging. [Journal Article]
- TTalanta 2016 Dec 1; 161:592-598
- Hypochlorous acid (HOCl) is a kind of reactive oxygen species which plays an important role in biological process. HOCl detection is of great importance in disease prevention and treatment. Herein, a...
Hypochlorous acid (HOCl) is a kind of reactive oxygen species which plays an important role in biological process. HOCl detection is of great importance in disease prevention and treatment. Herein, a cyanine-based near-infrared (NIR) fluorescent probe for HOCl has been designed and synthesized. This probe can react with HOCl in a dose-response manner along with the fluorescence of the probe quenched, the reaction through an electrophilic addition to the double bond and subsequent oxidation reaction. Experiments indicate that the probe can be acted as a selective and sensitive indicator for HOCl and the limit of detection for HOCl is estimated to be 22nM. What's more, this probe shows a low toxicity to cells and can be applied to visualize HOCl molecules in living cells. Therefore, the proposed method may make a significant contribution to HOCl detection.
New Search Next
- Novel bead-based platform for direct detection of unlabelled nucleic acids through Single Nucleobase Labelling. [Journal Article]
- TTalanta 2016 Dec 1; 161:489-496
- Over the last decade, circulating microRNAs have received attention as diagnostic and prognostic biomarkers. In particular, microRNA122 has been demonstrated to be an early and more sensitive indicat...
Over the last decade, circulating microRNAs have received attention as diagnostic and prognostic biomarkers. In particular, microRNA122 has been demonstrated to be an early and more sensitive indicator of drug-induced liver injury than the widely used biomarkers such as alanine aminotransferase and aspartate aminotransferase. Recently, microRNA122 has been used in vitro to assess the cellular toxicity of new drugs and as a biomarker for the development of a rapid test for drug overdose/liver damage. In this proof-of-concept study, we report a PCR-free and label-free detection method that has a limit of detection (3 standard deviations) of 15 fmoles of microRNA122, by integrating a dynamic chemical approach for "Single Nucleobase Labelling" with a bead-based platform (Luminex(®)) thereby, in principle, demonstrating the exciting prospect of rapid and accurate profiling of any microRNAs related to diseases and toxicology.