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(woven bone)
1,577 results
  • Exposure to Secondhand Smoke Impairs Fracture Healing in Rats. [Journal Article]
  • COClin Orthop Relat Res 2016 Nov 30
  • Santiago HA, Zamarioli A, … Volpon JB
  • CONCLUSIONS: Rats exposed to tobacco smoke showed delayed fracture healing and callus that was characterized by decreased maturity, density, and mechanical resistance, which was confirmed by all assessment methods of this study. Such effects were more evident when animals were exposed to tobacco smoke before and after the fracture. Future studies should be done in human passive smokers to confirm or refute our findings on fracture callus formation.The potential hazardous effects of secondhand smoke on fracture healing in rodents should stimulate future clinical studies in human passive smokers.
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