Contraindication/Precautions
Contraindicated in:
- Hypersensitivity to kanamycin or other aminoglycosides
- OB: Pregnancy.
Use Cautiously in:
- Renal impairment (dose adjustments necessary; blood level monitoring useful in preventing ototoxicity and nephrotoxicity)
- Hearing impairment
- Pedi: Geri: Geriatric patients and premature infants (difficulty in assessing auditory and vestibular function; age-related renal impairment)
- Pedi: Neonates (↑ risk of neuromuscular blockade; difficulty in assessing auditory and vestibular function; immature renal function)
- Neuromuscular diseases such as myasthenia gravis
- Lactation: Lactation (safety not established).
kanamycin has been found in Davis's Drug Guide
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