• If dose is ordered daily or every other day, administer in the morning to coincide with the body's normal secretion of cortisol.

• Periods of stress, such as surgery, may require supplemental systemic corticosteroids.

• PO: Administer with meals to minimize GI irritation.

» Tablets may be crushed and administered with food or fluids for patients with difficulty swallowing.

» Use calibrated measuring device to ensure accurate dosage of liquid forms.