Directly converts plasminogen to plasmin, which then degrades clot-bound fibrin.
Lysis of thrombi in coronary arteries, with improvement of ventricular function, and reduced risk of heart failure or death.
Lysis of pulmonary emboli.
Lysis of thrombi causing ischemic stroke, reducing risk of neurologic sequelae.
Restoration of cannula or catheter function.
alteplase has been found in Davis's Drug Guide
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