Pharmacokinetics
Absorption: Complete after IV administration. Intracoronary administration or administration into occluded catheters or cannulae has a more localized effect.
Distribution: Unknown.
Metabolism and Excretion: Rapidly metabolized by the liver.
Half-life: 35 min.
TIME/ACTION PROFILE (fibrinolysis)
| ROUTE | ONSET | PEAK | DURATION |
| IV | 30 mi | 60 min | unknown |
alteplase has been found in Davis's Drug Guide
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