Pharmacokinetics
Absorption: 45% absorbed from patch over 24 hr.
Distribution: Unknown.
Metabolism and Excretion: Mostly metabolized and excreted in urine as metabolites (71%); 11% excreted in feces.
Half-life: Biphasic: initial half-life 3 hr; terminal half-life 57 hr.
TIME/ACTION PROFILE
| ROUTE | ONSET | PEAK | DURATION |
| Transdermal | 13 hr | 1518 hr (rage 427 hr) | 24 hr |
rotigotine transdermal system has been found in Davis's Drug Guide
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