General Action Information
Converts plasminogen to plasmin, which then degrades fibrin in clots. Alteplase, reteplase, and urokinase directly activate plasminogen. Streptokinase binds with plasminogen to form activator complexes, which then convert plasminogen to plasmin. Results in lysis of thrombi in coronary arteries, pulmonary emboli, or deep vein thrombosis, or clearing of clots in cannulae/catheters.
thrombolytics has been found in Davis's Drug Guide
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