Absorption: Poorly absorbed following oral administration because of extensive first-pass hepatic metabolism, resulting in rapid conversion to albendazole sulfoxide, the active metabolite.
Distribution: Widely distributed.
Protein Binding: 70% bound to plasma proteins.
Metabolism and Excretion: After conversion to the sulfoxide metabolite, further hepatic metabolism to inactive compounds occurs. <1% excreted in urine; excretion is primarily via bile.
Half-life: Albendazole sulfoxide–8–12 hr.
TIME/ACTION PROFILE (blood levels of albendazole sulfoxide)
albendazole has been found in Davis's Drug Guide
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