Nursing Central: asparaginase

Davis's Drug Guide

asparaginase

Route/Dosage

• Various other regimens may be used

Multiple-Agent Induction Regimen (in Combination with Vincristine and Prednisone)

• IV (Children): 1000 IU/kg/day for 10 successive days beginning on day 22 of regimen..

• IM (Children): 6000 IU/m² on days 4, 7, 10, 13, 16, 19, 22, 25, 28..

Single-Agent Therapy for Acute Lymphocytic Leukemia

• IV (Adults and Children): 200 IU/kg daily for 28 days..

Desensitization Regimen

• IV (Adults and Children): Administer 1 IU, then double dose every 10 min until total dose for that day has been given or reaction occurs..

Test Dose

• Intradermal (Adults and Children): 2 IU..

asparaginase has been found in Davis's Drug Guide

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