Monitor ECG, heart rate, color, chest expansion, facial expression, transcutaneous oxygen saturation, and endotracheal tube patency continuously during dosing. Continuous bedside monitoring should continue for at least 30 min after dosing.Lab Test Considerations
Monitor ABGs frequently to prevent hyperoxia or hypocarbia.Toxicity and Overdose
If chest expansion improves substantially after dosing, reduce peak inspiratory ventilator pressures immediately to prevent lung overdistention and fatal pulmonary leak.
» If infant becomes pink and transcutaneous oxygen saturation is in excess of 95%, reduce FIO2 in small but repeated steps immediately to prevent hyperoxia.
» If arterial or transcutaneous CO2 measurements are less than 30 mm Hg, ventilator rate should be reduced immediately to prevent hypocarbia.
colfosceril palmitate has been found in Davis's Drug Guide
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