Nursing Central: desmopressin

desmopressin

Route/Dosage

Primary Nocturnal Enuresis

• PO (Adults and Children ≥6 yr): 0.2 mg at bedtime; may be titrated up to 0.6 mg at bedtime to achieve desired response..

Diabetes Insipidus

• PO (Adults and Children): 0.05 mg twice daily; adjusted as needed (usual range: 0.1–1.2 mg/day for adults or 0.1–0.8 mg/day for children in 2–3 divided doses)..

• Intranasal (Adults and Children ≥ 12 yr): DDAVP–5–40 mcg (0.0.05–0.4 mL)in 1–3 divided doses..

• Intranasal (Children 3 mo–12 yr): DDAVP–5–30 mcg (0.05–0.3 mL) in 1–2 divided doses..

• SC, IV (Adults and Children≥12 yr): 2–4 mcg/day in 2 divided doses..

• SC, IV (Children < 12 yr): 0.1–1 mcg/day in 1–2 divided doses..

Hemophilia A/von Willebrand's disease

• Intranasal (Adults and Children >50 kg): Stimate—1 spray (150 mcg) in each nostril..

• Intranasal (Adults and Children ≤50 kg): Stimate—1 spray (150 mcg) in one nostril..

• IV (Adults and Children >3 mo): 0.3 mcg/kg, repeated as needed..

desmopressin has been found in Davis's Drug Guide

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