Oropharyngeal Candidiasis

• PO, IV (Adults): 200 mg initially, then 100 mg daily for at least 2 wk..

• PO, IV (Children >14 days): 6 mg/kg initially, then 3 mg/kg/day for at least 2 wk..

• PO, IV (Neonates <14 days, 30–36 weeks gestation): same dose as older children except frequency is q 48 hr; Premature neonates <29 weeks gestation: 5–6 mg/kg/dose q 48–72 hr..

• PO, IV (Adults): 200 mg initially, then 100 mg once daily for at least 3 wk (up to 400 mg/day)..

• PO, IV (Children >14 days): 6 mg/kg initially, then 3–12 mg/kg/day for at least 3 wk..

• PO, IV (Neonates <14 days, 30–36 weeks gestation): same dose as older children except frequency is q 48 hr; Premature neonates <29 weeks gestation: 5–6 mg/kg/dose q 48–72 hr..

• PO (Adults): 150-mg single dose; prevention of recurrence (unlabeled)—150 mg daily for 3 days then weekly for 6 mo..

• PO, IV (Adults): 400 mg/day initially, then 200–800 mg/day for 28 days..

• PO, IV (Children > 14 days): 6–12 mg/kg/day for 28 days..

• PO, IV (Neonates <14 days, 30–36 weeks gestation): same dose as older children except frequency is q 48 hr; Premature neonates <29 weeks gestation: 5–6 mg/kg/dose q 48–72 hr..

• PO, IV (Adults): Treatment—400 mg once daily until favorable clinical response, then 200–800 mg once daily for at least 10–12 wk after clearing of CSF; change to oral therapy as soon as possible. Suppressive therapy—200 mg once daily..

• PO, IV (Children >14 days): 12 mg/kg/day initially, then 6–12 mg/kg/day for at least 10–12 wk after clearing of CSF; change to oral therapy as soon as possible. Suppressive therapy—6 mg/kg/day..

• PO, IV (Neonates <14 days, 30–36 weeks gestation): same dose as older children except frequency is q 48 hr; Premature neonates <29 weeks gestation: 5–6 mg/kg/dose q 48–72 hr..

• PO, IV (Adults): 400 mg once daily; begin several days before procedure if severe neutropenia is expected, and continue for 7 days after ANC >1000 /mm³..

• PO, IV (Children >14 days): 10–12 mg/kg/day, not to exceed 600 mg/day..

• PO, IV (Adults): CCr 11–50 mL/min—50% of the usual dose..