Davis's Drug Guide
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mesna

Implementation

  • Initial IV bolus is to be given at time of ifosfamide administration.
  • PO: If second and third doses are given orally, administer 2 and 6 hours after IV dose.
    • If PO mesna is vomited within 2 hr of administration, repeat dose or use IV mesna.
  • Syringe Compatibility
    • ifosfamide
  • Y-Site Compatibility
    • allopurinol
    • amifostine
    • aztreonam
    • cefepime
    • docetaxel
    • doxorubicin liposome
    • etoposide phosphate
    • filgrastim
    • fludarabine
    • gemcitabine
    • granisetron
    • linezolid
    • melphalan
    • methotrexate
    • ondansetron
    • oxaliplatin
    • paclitaxel
    • pemetrexed
    • piperacillin/tazobactam
    • sargramostim
    • sodium bicarbonate
    • teniposide
    • thiotepa
    • vinorelbine
  • Y-Site Incompatibility
    • amphotericin B cholesteryl complex
    • lansoprazole
  • Additive Compatibility
    • ifosfamide
  • Additive Incompatibility
    • carboplatin
    • cisplatin
  • Rate: Administer over 15–30 min or as a continuous infusion.
  • Syringe Compatibility
    • ifosfamide
  • Y-Site Compatibility
    • allopurinol
    • amifostine
    • aztreonam
    • cefepime
    • docetaxel
    • doxorubicin liposome
    • etoposide phosphate
    • filgrastim
    • fludarabine
    • gemcitabine
    • granisetron
    • linezolid
    • melphalan
    • methotrexate
    • ondansetron
    • oxaliplatin
    • paclitaxel
    • pemetrexed
    • piperacillin/tazobactam
    • sargramostim
    • sodium bicarbonate
    • teniposide
    • thiotepa
    • vinorelbine
  • Y-Site Incompatibility
    • amphotericin B cholesteryl complex
    • lansoprazole
  • Additive Compatibility
    • ifosfamide
  • Additive Incompatibility
    • carboplatin
    • cisplatin

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