• Monitor BP every 2–3 min until stabilized and every 5 min thereafter during IV administration.

» Monitor ECG continuously for arrhythmias during IV administration.

» Assess IV site frequently throughout infusion. Antecubital or other large vein should be used to minimize risk of extravasation, which may cause tissue necrosis. If extravasation occurs, the site should be infiltrated promptly with 10–15 mL of 0.9% NaCl solution containing 5–10 mg of phentolamine to prevent necrosis and sloughing.