May ↓ efficacy of hormonal contraceptives .
Strong CYP2C8 inhibitors , including gemfibrozil may ↑ levels.
Ketoconazole may ↑ effects of pioglitazone. Concurrent use with insulin may ↑ risk of HF (consider predisposing factors).Drug-Natural Products
Glucosamine may worsen blood glucose control.
Chromium , and coenzyme Q-10 may produce ↑ hypoglycemic effects.
pioglitazone has been found in Davis's Drug Guide
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